Detalhe da pesquisa
1.
Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-ß-alanine (FBAL).
Pharmazie
; 78(8): 107-112, 2023 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37592424
2.
Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study.
Ann Oncol
; 33(10): 1071-1082, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35777707
3.
Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.
Drug Metab Dispos
; 50(4): 327-340, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35042701
4.
A real or apparent decrease in glomerular filtration rate in patients using olaparib?
Eur J Clin Pharmacol
; 77(2): 179-188, 2021 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-33319340
5.
Development and validation of an LC-MS/MS method for the quantification of imatinib and imatinib-d8 in human plasma for the support of an absolute bioavailability microdose trial.
Pharmazie
; 75(4): 136-141, 2020 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32295689
6.
Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.
Ann Oncol
; 30(2): 219-235, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30608567
7.
ABC transporters Mdr1a/1b, Bcrp1, Mrp2 and Mrp3 determine the sensitivity to PhIP/DSS-induced colon carcinogenesis and inflammation.
Arch Toxicol
; 93(3): 775-790, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30701287
8.
Cost-effectiveness of monitoring endoxifen levels in breast cancer patients adjuvantly treated with tamoxifen.
Breast Cancer Res Treat
; 172(1): 143-150, 2018 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-30006796
9.
Development and validation of a liquid chromatography-tandem mass spectrometry analytical method for the therapeutic drug monitoring of eight novel anticancer drugs.
Biomed Chromatogr
; 32(4)2018 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-29165815
10.
DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.
Ann Oncol
; 28(12): 2915-2922, 2017 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29045513
11.
An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.
Breast Cancer Res Treat
; 161(3): 567-574, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28005246
12.
Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies.
Pharmacogenomics J
; 17(5): 441-451, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27995989
13.
Metabolism and disposition of the anticancer quinolone derivative vosaroxin, a novel inhibitor of topoisomerase II.
Invest New Drugs
; 35(4): 478-490, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28138829
14.
Pharmacokinetics and excretion of 14C-Plitidepsin in patients with advanced cancer.
Invest New Drugs
; 35(5): 589-598, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28111728
15.
Human mass balance study and metabolite profiling of 14C-niraparib, a novel poly(ADP-Ribose) polymerase (PARP)-1 and PARP-2 inhibitor, in patients with advanced cancer.
Invest New Drugs
; 35(6): 751-765, 2017 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28303528
16.
Development and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma.
Ther Drug Monit
; 39(3): 243-251, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28490047
17.
Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies.
Drug Dev Ind Pharm
; 43(4): 584-594, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28010129
18.
Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection.
Antimicrob Agents Chemother
; 60(4): 2081-9, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26787691
19.
Regulatory aspects of human radiolabeled mass balance studies in oncology: concise review.
Drug Metab Rev
; 48(2): 266-80, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27186889
20.
Pharmacodynamic modeling of adverse effects of anti-cancer drug treatment.
Eur J Clin Pharmacol
; 72(6): 645-53, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-26915815