Detalhe da pesquisa
1.
Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.
Nat Immunol
; 23(9): 1379-1392, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36002648
2.
AATF/Che-1 localizes to paraspeckles and suppresses R-loops accumulation and interferon activation in Multiple Myeloma.
EMBO J
; 41(22): e109711, 2022 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35929179
3.
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.
Cell
; 146(1): 67-79, 2011 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21722948
4.
Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Nucleic Acids Res
; 48(11): 5891-5906, 2020 06 19.
Artigo
Inglês
| MEDLINE | ID: mdl-32421830
5.
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.
EMBO Rep
; 19(3)2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29367285
6.
Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
EMBO J
; 34(9): 1214-30, 2015 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25770584
7.
Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization.
J Biol Chem
; 288(32): 23348-57, 2013 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-23798705
8.
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Cancer Cell
; 10(6): 473-86, 2006 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17157788
9.
Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb.
Cancer Cell
; 2(5): 387-99, 2002 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-12450794
10.
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
Nat Cell Biol
; 4(1): 11-9, 2002 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-11780126
11.
CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity.
J Exp Clin Cancer Res
; 40(1): 232, 2021 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34266450
12.
Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma.
Blood Adv
; 4(22): 5616-5630, 2020 11 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33186461
13.
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease.
Leukemia
; 38(4): 877-882, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38368441
14.
Che-1 enhances cyclin-dependent kinase 5 expression and interacts with the active kinase-complex.
Neuroreport
; 19(5): 531-5, 2008 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-18388733
15.
Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.
J Exp Clin Cancer Res
; 36(1): 32, 2017 02 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28214471
16.
Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins.
Front Oncol
; 6: 34, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26913241
17.
Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.
Oncotarget
; 7(43): 70546-70558, 2016 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-27655709
18.
The alpha-like RNA polymerase II core subunit 3 (RPB3) is involved in tissue-specific transcription and muscle differentiation via interaction with the myogenic factor myogenin.
FASEB J
; 16(12): 1639-41, 2002 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12207009
19.
Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.
Clin Cancer Res
; 10(22): 7747-56, 2004 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15570009
20.
Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.
Cancer Res
; 75(21): 4560-72, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26359458