Detalhe da pesquisa
1.
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.
Proc Natl Acad Sci U S A
; 121(7): e2315069121, 2024 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38315851
2.
Wolbachia infection negatively impacts Drosophila simulans heat tolerance in a strain- and trait-specific manner.
Environ Microbiol
; 26(4): e16609, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38558489
3.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc Natl Acad Sci U S A
; 116(19): 9318-9323, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30962368
4.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc Natl Acad Sci U S A
; 116(14): 7015-7020, 2019 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30894487
5.
Microplastic concentrations and risk assessment in water, sediment and invertebrates from Simon's Town, South Africa.
Heliyon
; 10(7): e28514, 2024 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38586395
6.
The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes.
Microb Cell
; 10(2): 18-35, 2023 Feb 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36789350
7.
Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
J Med Chem
; 66(15): 10413-10431, 2023 08 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37506194
8.
Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.
Eur J Med Chem
; 238: 114421, 2022 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35594652
9.
Outcomes in patients with fractured ribs: middle aged at same risk of complications as the elderly.
N Z Med J
; 134(1540): 38-45, 2021 08 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34482387
10.
Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).
ACS Med Chem Lett
; 10(3): 341-347, 2019 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30891137
11.
Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.
J Med Chem
; 61(15): 6592-6608, 2018 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29944372
12.
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.
ACS Infect Dis
; 4(6): 954-969, 2018 06 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29522317