Detalhe da pesquisa
1.
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Res
; 48(21): 12234-12251, 2020 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33211885
2.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Nature
; 508(7495): 222-7, 2014 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24695225
3.
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature
; 508(7495): 215-21, 2014 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24695224
4.
Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature
; 544(7651): 508, 2017 04 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28447629
5.
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Nat Cancer
; 3(2): 156-172, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35228749
6.
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Cancer Res
; 81(22): 5733-5744, 2021 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34593524
7.
Karonudib is a promising anticancer therapy in hepatocellular carcinoma.
Ther Adv Med Oncol
; 11: 1758835919866960, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31489034
8.
A novel method for quantification of the folding of elastic laminae in elastic arteries.
Micron
; 39(5): 623-30, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17485215
9.
Serotonin transporter (5-HTTLPR) and monoamine oxidase (MAOA) promoter polymorphisms in women with severe alcoholism.
Arch Womens Ment Health
; 11(5-6): 347-55, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18827956
10.
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science
; 362(6416): 834-839, 2018 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30442810
11.
Macrovascular changes in mice overexpressing human semicarbazide-sensitive amine oxidase in smooth muscle cells.
Am J Hypertens
; 20(7): 743-50, 2007 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17586408
12.
Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma.
J Pharm Biomed Anal
; 104: 1-11, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25459754
13.
SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways.
Cell Cycle
; 12(24): 3770-80, 2013 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24107632
14.
The clock gene PER2 and sleep problems: association with alcohol consumption among Swedish adolescents.
Ups J Med Sci
; 115(1): 41-8, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20187847
15.
Two repeated maternal separation procedures differentially affect brain 5-hydroxytryptamine transporter and receptors in young and adult male and female rats.
Brain Res
; 1305 Suppl: S37-49, 2009 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-19728999
16.
The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents.
Obesity (Silver Spring)
; 17(9): 1762-7, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19325541
17.
Transcription factor AP2 beta involved in severe female alcoholism.
Brain Res
; 1305 Suppl: S20-6, 2009 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-19778525
18.
Semicarbazide-sensitive amine oxidase (SSAO) gene expression in alloxan-induced diabetes in mice.
Mol Med
; 8(12): 824-9, 2002 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-12606817
19.
Overexpression of semicarbazide-sensitive amine oxidase in smooth muscle cells leads to an abnormal structure of the aortic elastic laminas.
Am J Pathol
; 163(5): 1921-8, 2003 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-14578191