Detalhe da pesquisa
1.
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
Nat Immunol
; 16(1): 75-84, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25347465
2.
Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer's Disease and Multiple Sclerosis.
J Neurosci
; 2024 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38830764
3.
Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Proc Natl Acad Sci U S A
; 116(33): 16420-16429, 2019 08 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31371506
4.
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aß42:Aß40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
J Neurosci
; 40(9): 1956-1974, 2020 02 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31980586
5.
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display.
Proc Natl Acad Sci U S A
; 112(18): 5679-84, 2015 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25902490
6.
Chronic GluN2B antagonism disrupts behavior in wild-type mice without protecting against synapse loss or memory impairment in Alzheimer's disease mouse models.
J Neurosci
; 34(24): 8277-88, 2014 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24920631
7.
A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
J Neurosci
; 34(19): 6425-37, 2014 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24806669
8.
A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity.
Cell Rep Methods
; 4(1): 100673, 2024 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38171361
9.
An effector-reduced anti-ß-amyloid (Aß) antibody with unique aß binding properties promotes neuroprotection and glial engulfment of Aß.
J Neurosci
; 32(28): 9677-89, 2012 Jul 11.
Artigo
Inglês
| MEDLINE | ID: mdl-22787053
10.
Combined PD-L1/TGFß blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors.
Nat Commun
; 14(1): 4703, 2023 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37543621
11.
Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms.
Arterioscler Thromb Vasc Biol
; 31(2): 270-9, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21071686
12.
Dual targeting of lymphocyte homing and retention through α4ß7 and αEß7 inhibition in inflammatory bowel disease.
Cell Rep Med
; 2(8): 100381, 2021 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34467254
13.
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J Exp Med
; 218(4)2021 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33620419
14.
Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage.
Commun Biol
; 3(1): 687, 2020 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33214666
15.
Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models.
Cancer Res
; 67(10): 4924-32, 2007 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17510422
16.
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Cell Rep
; 28(8): 2111-2123.e6, 2019 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31433986
17.
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models.
Cancer Res
; 66(2): 999-1006, 2006 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16424035
18.
pHUSH: a single vector system for conditional gene expression.
BMC Biotechnol
; 7: 61, 2007 Sep 26.
Artigo
Inglês
| MEDLINE | ID: mdl-17897455
19.
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Sci Transl Med
; 9(403)2017 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28814543
20.
Reduced aversion to oral capsaicin following neurotoxic destruction of superficial medullary neurons expressing NK-1 receptors.
Brain Res
; 945(1): 139-43, 2002 Jul 26.
Artigo
Inglês
| MEDLINE | ID: mdl-12113962