Detalhe da pesquisa
1.
Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype.
Microcirculation
; 31(2): e12840, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38082450
2.
Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia-Reperfusion.
Int J Mol Sci
; 23(6)2022 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-35328832
3.
Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model.
J Cell Mol Med
; 24(2): 1738-1749, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31863639
4.
OKlahoma Nitrone-007: novel treatment for diffuse intrinsic pontine glioma.
J Transl Med
; 18(1): 424, 2020 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33168005
5.
Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates.
Molecules
; 21(11)2016 Oct 26.
Artigo
Inglês
| MEDLINE | ID: mdl-27792200
6.
Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence.
Nutrients
; 16(7)2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38612986
7.
Whole brain irradiation-induced endothelial dysfunction in the mouse brain.
Geroscience
; 46(1): 531-541, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-37953375
8.
Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence.
Geroscience
; 46(3): 3105-3122, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38182857
9.
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
Geroscience
; 46(1): 21-37, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38044400
10.
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages.
Geroscience
; 2024 Apr 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38639833
11.
Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors.
Geroscience
; 46(1): 327-347, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38123890
12.
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain.
Geroscience
; 2024 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38727872
13.
Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis.
Front Endocrinol (Lausanne)
; 14: 1087053, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36755922
14.
The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment.
Nutrients
; 15(21)2023 Nov 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37960316
15.
Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin.
Geroscience
; 45(5): 2851-2872, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37338779
16.
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
Aging Cell
; 22(7): e13832, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37243381
17.
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.
Geroscience
; 45(6): 3381-3408, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37688657
18.
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
Geroscience
; 45(5): 2983-3002, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37642933
19.
XRN2 Is Required for Cell Motility and Invasion in Glioblastomas.
Cells
; 11(9)2022 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35563787
20.
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
Geroscience
; 44(2): 661-681, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35098444