Detalhe da pesquisa
1.
Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
J Biol Chem
; 293(13): 4870-4882, 2018 03 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29440396
2.
Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids.
Mol Genet Genomics
; 290(2): 505-11, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25325994
3.
1,25-dihydroxyvitamin d3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells.
Biol Reprod
; 89(6): 150, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24174578
4.
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
Hum Reprod
; 28(9): 2407-16, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23814095
5.
1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model.
Biol Reprod
; 86(4): 116, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22302692
6.
Antimetastatic role of Smad4 signaling in colorectal cancer.
Gastroenterology
; 138(3): 969-80.e1-3, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19909744
7.
Introduction of Somatic Mutation in MED12 Induces Wnt4/ß-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell.
Reprod Sci
; 27(3): 823-832, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32046450
8.
Oncogenic serine-threonine kinase receptor-associated protein modulates the function of Ewing sarcoma protein through a novel mechanism.
Cancer Res
; 66(22): 10824-32, 2006 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17108118
9.
Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis.
Cancer Res
; 66(12): 6156-66, 2006 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16778189
10.
Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas.
J Clin Endocrinol Metab
; 103(11): 4283-4292, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30099503
11.
Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells.
Cell Signal
; 18(7): 1041-50, 2006 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16288847
12.
Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/ß-Catenin Signaling Pathway.
Endocrinology
; 158(3): 592-603, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27967206
13.
Vitamin D3 Inhibits Wnt/ß-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells.
J Clin Endocrinol Metab
; 101(4): 1542-51, 2016 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26820714
14.
A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers.
Neoplasia
; 7(5): 509-21, 2005 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15967103
15.
A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).
Mol Endocrinol
; 16(8): 1853-63, 2002 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12145339
16.
1,25-dihydroxyvitamin D3 regulates expression of sex steroid receptors in human uterine fibroid cells.
J Clin Endocrinol Metab
; 100(4): E572-82, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25625804
17.
Role of vitamin D in uterine fibroid biology.
Fertil Steril
; 104(3): 698-706, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26079694
18.
Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids.
Reprod Sci
; 21(9): 1108-19, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24925855
19.
Role of TGF-ß signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells.
J Cancer Res Clin Oncol
; 139(4): 563-72, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23224523
20.
Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study.
Int J Womens Health
; 5: 93-100, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23467803