Detalhe da pesquisa
1.
CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-ß mimic.
Proc Natl Acad Sci U S A
; 120(34): e2302370120, 2023 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37590410
2.
Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-ß to its receptors, TßRI and TßRII.
J Biol Chem
; 298(6): 101994, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35500648
3.
TGFß carrying exosomes in plasma: potential biomarkers of cancer progression in patients with head and neck squamous cell carcinoma.
Br J Cancer
; 128(9): 1733-1741, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36810911
4.
Synthesis of 13C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells.
Org Biomol Chem
; 21(46): 9216-9229, 2023 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37964666
5.
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Proc Natl Acad Sci U S A
; 116(31): 15505-15513, 2019 07 30.
Artigo
Inglês
| MEDLINE | ID: mdl-31315975
6.
TGF-ß2 uses the concave surface of its extended finger region to bind betaglycan's ZP domain via three residues specific to TGF-ß and inhibin-α.
J Biol Chem
; 294(9): 3065-3080, 2019 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30598510
7.
Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat Methods
; 14(4): 399-402, 2017 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-28192420
8.
Mechanism of the Flavoprotein d-6-Hydroxynicotine Oxidase: Substrate Specificity, pH and Solvent Isotope Effects, and Roles of Key Active-Site Residues.
Biochemistry
; 58(21): 2534-2541, 2019 05 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31046245
9.
An engineered transforming growth factor ß (TGF-ß) monomer that functions as a dominant negative to block TGF-ß signaling.
J Biol Chem
; 292(17): 7173-7188, 2017 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28228478
10.
In Search of "Hepatic Factor": Lack of Evidence for ALK1 Ligands BMP9 and BMP10.
Am J Respir Crit Care Med
; 203(2): 249-251, 2021 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32871084
11.
Mechanism of the Flavoprotein L-Hydroxynicotine Oxidase: Kinetic Mechanism, Substrate Specificity, Reaction Product, and Roles of Active-Site Residues.
Biochemistry
; 55(4): 697-703, 2016 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26744768
12.
Binding Properties of the Transforming Growth Factor-ß Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
Biochemistry
; 55(49): 6880-6896, 2016 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27951653
13.
The regulatory domain of human tryptophan hydroxylase 1 forms a stable dimer.
Biochem Biophys Res Commun
; 476(4): 457-461, 2016 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27255998
14.
Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active site.
Biochemistry
; 53(49): 7846-53, 2014 Dec 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25453233
15.
Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells.
Cells
; 13(3)2024 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38334677
16.
Design of High Affinity Binders to Convex Protein Target Sites.
bioRxiv
; 2024 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38746206
17.
The helminth TGF-ß mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-ß receptors to preferentially target myeloid cells.
bioRxiv
; 2023 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38014296
18.
TGM6, a helminth secretory product, mimics TGF-ß binding to TßRII to antagonize TGF-ß signaling in fibroblasts.
bioRxiv
; 2023 Dec 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38187573
19.
Correction to Binding Properties of the Transforming Growth Factor-ß Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
Biochemistry
; 56(28): 3689, 2017 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28677957
20.
TGFß+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro-angiogenic phenotype.
J Extracell Vesicles
; 11(12): e12294, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36537293