Detalhe da pesquisa
1.
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.
J Biol Chem
; 299(7): 104890, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37286039
2.
CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2.
Biochem Biophys Res Commun
; 562: 146-153, 2021 07 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34052660
3.
Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.
Biochem Biophys Res Commun
; 523(2): 354-360, 2020 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31866012
4.
C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity.
J Atheroscler Thromb
; 31(2): 109-116, 2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37793810
5.
Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia.
J Atheroscler Thromb
; 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38538338
6.
Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic ß cell function.
Cell Rep
; 42(8): 112914, 2023 08 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37557182
7.
Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids.
PNAS Nexus
; 2(11): pgad351, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37954160
8.
The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis.
Nat Commun
; 12(1): 6315, 2021 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34728642