Detalhe da pesquisa
1.
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.
Cell
; 154(3): 691-703, 2013 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23890820
2.
Delineation of dominant and recessive forms of LZTR1-associated Noonan syndrome.
Clin Genet
; 95(6): 693-703, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30859559
3.
Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons.
Genomics
; 110(2): 98-111, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28911974
4.
Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.
Genome Med
; 15(1): 94, 2023 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37946251
5.
Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.
J Proteome Res
; 11(2): 631-42, 2012 Feb 03.
Artigo
Inglês
| MEDLINE | ID: mdl-22029865
6.
Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.
J Proteome Res
; 10(4): 1675-89, 2011 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21322573
7.
Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat.
Mamm Genome
; 21(9-10): 499-508, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20878524
8.
Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes.
BMC Genomics
; 10: 63, 2009 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-19196459
9.
Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance.
Dis Model Mech
; 12(7)2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31213483
10.
Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.
Cancers (Basel)
; 11(12)2019 Nov 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31795195
11.
Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat.
Eur J Med Genet
; 51(4): 325-31, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18434273
12.
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.
J Med Genet
; 44(9): 603-5, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17557929
13.
Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Lancet Gastroenterol Hepatol
; 3(9): 635-643, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30042065
14.
Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression.
G3 (Bethesda)
; 6(11): 3671-3683, 2016 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27646706
15.
Targeted Next-Generation Sequencing of Plasma DNA from Cancer Patients: Factors Influencing Consistency with Tumour DNA and Prospective Investigation of Its Utility for Diagnosis.
PLoS One
; 11(9): e0162809, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27626278
16.
Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome.
Diabetes
; 53(7): 1900-4, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15220217
17.
Quantitative trait locus dissection in congenic strains of the Goto-Kakizaki rat identifies a region conserved with diabetes loci in human chromosome 1q.
Physiol Genomics
; 19(1): 1-10, 2004 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-15266047
18.
Genetic control of differential acetylation in diabetic rats.
PLoS One
; 9(4): e94555, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24743600
19.
MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes.
BMC Med Genomics
; 2: 54, 2009 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-19689793
20.
Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.
BMC Med Genomics
; 2: 41, 2009 Jul 09.
Artigo
Inglês
| MEDLINE | ID: mdl-19586551