Detalhe da pesquisa
1.
B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
Cell
; 173(2): 470-484.e18, 2018 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29551267
2.
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.
Mol Cell
; 81(10): 2094-2111.e9, 2021 05 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33878293
3.
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
Nat Immunol
; 16(7): 766-774, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25985233
4.
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells.
Nature
; 588(7838): 491-497, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33149299
5.
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally.
Nature
; 567(7748): 414-419, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30867593
6.
Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia.
Blood
; 136(2): 210-223, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32219444
7.
Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells.
Nature
; 592(7852): E3, 2021 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-33712811
8.
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Nature
; 521(7552): 357-61, 2015 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25799995
9.
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition.
Nature
; 473(7347): 384-8, 2011 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-21593872
10.
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Nature
; 534(7605): 138, 2016 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26958840
11.
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.
Blood
; 121(10): 1814-8, 2013 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23319569
12.
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Blood
; 118(8): 2191-9, 2011 Aug 25.
Artigo
Inglês
| MEDLINE | ID: mdl-21715311
13.
Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.
Nat Commun
; 6: 6471, 2015 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25753524
14.
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia.
Cancer Cell
; 28(1): 114-28, 2015 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26073130
15.
AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine.
Oncotarget
; 5(1): 211-23, 2014 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24457556
16.
Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: implications for the timing of the breaks in the t(14;18) translocation.
Mol Cell Biol
; 33(5): 947-57, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23263985
17.
Vitamin D protects acute lymphoblastic leukemia cells from dexamethasone.
Leuk Res
; 36(5): 591-3, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22341429
18.
Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models.
Cancer Prev Res (Phila)
; 3(10): 1259-64, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20823291
19.
BCL6 is critical for the development of a diverse primary B cell repertoire.
J Exp Med
; 207(6): 1209-21, 2010 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-20498019
20.
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.
Cancer Cell
; 16(3): 232-45, 2009 Sep 08.
Artigo
Inglês
| MEDLINE | ID: mdl-19732723