Detalhe da pesquisa
1.
Control of tissue oxygenation by S-nitrosohemoglobin in human subjects.
Proc Natl Acad Sci U S A
; 120(9): e2220769120, 2023 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36812211
2.
LMX1B mutations cause hereditary FSGS without extrarenal involvement.
J Am Soc Nephrol
; 24(8): 1216-22, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23687361
3.
Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction.
J Gerontol A Biol Sci Med Sci
; 78(Suppl 1): 32-37, 2023 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36738276
4.
A Study to Evaluate Relative Bioavailability, Food Effect, and Pharmacodynamics of Tropifexor, a Farnesoid X Receptor Agonist, in Healthy Participants.
Clin Pharmacol Drug Dev
; 12(2): 122-131, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36495282
5.
Synergistic Strategies to Accelerate the Development of Function-Promoting Therapies: Lessons From Operation Warp Speed and Oncology Drug Development.
J Gerontol A Biol Sci Med Sci
; 78(Suppl 1): 94-100, 2023 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37325963
6.
Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation.
BMC Pulm Med
; 12: 34, 2012 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-22818364
7.
Farnesoid X receptor agonist tropifexor attenuates cholestasis in a randomised trial in patients with primary biliary cholangitis.
JHEP Rep
; 4(11): 100544, 2022 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-36267872
8.
Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials.
Lancet Healthy Longev
; 2(5): e250-e262, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33977284
9.
Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Cell Chem Biol
; 28(9): 1271-1282.e12, 2021 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33894161
10.
Ligation of erythrocyte CR1 induces its clustering in complex with scaffolding protein FAP-1.
Blood
; 112(8): 3465-73, 2008 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18684861
11.
Matrix metalloproteinase-9-mediated type III collagen degradation as a novel serological biochemical marker for liver fibrogenesis.
Liver Int
; 30(9): 1293-304, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20666994
12.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non-Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 9(3): 395-410, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31823525
13.
Tropifexor-Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents.
Hepatol Commun
; 3(8): 1085-1097, 2019 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-31388629
14.
Characterization of two novel LPS-binding sites in leukocyte integrin betaA domain.
FASEB J
; 21(12): 3231-9, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17522381
15.
TORC1 inhibition enhances immune function and reduces infections in the elderly.
Sci Transl Med
; 10(449)2018 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29997249
16.
Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
J Gerontol A Biol Sci Med Sci
; 73(7): 845-852, 2018 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29304191
17.
Urinary Monocyte Chemoattractant Protein-1 in Patients With Alport Syndrome.
Kidney Int Rep
; 7(5): 1112-1114, 2022 May.
Artigo
Inglês
| MEDLINE | ID: mdl-35571002
18.
Evaluation of an Automated Falls Detection Device in Nursing Home Residents.
J Am Geriatr Soc
; 64(2): 365-8, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26783046
19.
A role for lipid rafts in C1q-triggered O2- generation by human neutrophils.
Mol Immunol
; 41(2-3): 185-90, 2004 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15159064
20.
A comparison of type I collagen, fibronectin, and vitronectin in supporting adhesion of mechanically strained osteoblasts.
J Bone Miner Res
; 17(3): 481-92, 2002 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-11874239