Detalhe da pesquisa
1.
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.
Cell
; 171(3): 696-709.e23, 2017 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-28965760
2.
PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Nature
; 576(7785): 138-142, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31748741
3.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Nat Chem Biol
; 16(9): 997-1005, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32514184
4.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
J Biol Chem
; 295(18): 5891-5905, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32152231
5.
Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation.
Nat Chem Biol
; 14(1): 22-28, 2018 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29131145
6.
Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity.
J Biol Chem
; 289(15): 10876-10886, 2014 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24558042
7.
Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice.
FASEB J
; 28(6): 2655-66, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24599971
8.
Differential regulation of the expressions of the PGC-1α splice variants, lipins, and PPARα in heart compared to liver.
J Lipid Res
; 54(6): 1662-1677, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23505321
9.
Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice.
J Lipid Res
; 53(1): 105-18, 2012 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-22058427
10.
Myocardial fatty acid metabolism and lipotoxicity in the setting of insulin resistance.
Heart Fail Clin
; 8(4): 643-61, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22999246
11.
Drug-Initiated Activity Metabolomics Identifies Myristoylglycine as a Potent Endogenous Metabolite for Human Brown Fat Differentiation.
Metabolites
; 12(8)2022 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36005620
12.
Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity.
Nat Commun
; 13(1): 608, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35105890
13.
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
Nat Commun
; 13(1): 4099, 2022 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35835746
14.
Isolation and Differentiation of Primary White and Brown Preadipocytes from Newborn Mice.
J Vis Exp
; (167)2021 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33554974
15.
Metabolomics activity screening of T cell-induced colitis reveals anti-inflammatory metabolites.
Sci Signal
; 14(702): eabf6584, 2021 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34582249
16.
A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.
J Biol Chem
; 284(43): 29968-78, 2009 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-19717560
17.
Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization.
Am J Physiol Endocrinol Metab
; 298(5): E897-908, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20103741
18.
Unlike two peas in a pod: lipid phosphate phosphatases and phosphatidate phosphatases.
Chem Rev
; 112(10): 5121-46, 2012 Oct 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22742522
19.
Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments.
Methods Mol Biol
; 1787: 115-127, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29736714
20.
Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits.
Mol Metab
; 16: 76-87, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30120064