1.
Cell Stem Cell
; 23(1): 21-24, 2018 07 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29887317
RESUMO
The genetic complexity, clinical variability, and inaccessibility of affected tissue in neurodegenerative and neuropsychiatric disorders have largely prevented the development of effective disease-modifying therapeutics. A precision medicine approach that integrates genomics, deep clinical phenotyping, and patient stem cell models may facilitate identification of underlying biological drivers and targeted drug development.