Detalhe da pesquisa
1.
Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans.
Xenobiotica
; 50(9): 1101-1114, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-31902291
2.
Neuropilin-1 drives tumor-specific uptake of chlorotoxin.
Cell Commun Signal
; 17(1): 67, 2019 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31208428
3.
Pharmacokinetic/pharmacodynamic drug-drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs.
Br J Clin Pharmacol
; 84(5): 952-960, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29341245
4.
Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor.
Drug Metab Dispos
; 45(2): 183-189, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27934636
5.
Contribution of metabolites to P450 inhibition-based drug-drug interactions: scholarship from the drug metabolism leadership group of the innovation and quality consortium metabolite group.
Drug Metab Dispos
; 43(4): 620-30, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25655830
6.
Reversible inhibition of human carboxylesterases by acyl glucuronides.
Drug Metab Dispos
; 41(4): 698-703, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23386702
7.
Metabolic switching of BILR 355 in the presence of ritonavir. II. Uncovering novel contributions by gut bacteria and aldehyde oxidase.
Drug Metab Dispos
; 40(6): 1130-7, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22393121
8.
Metabolic switching of BILR 355 in the presence of ritonavir. I. Identifying an unexpected disproportionate human metabolite.
Drug Metab Dispos
; 40(6): 1122-9, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22393120
9.
A Baeyer-Villiger oxidation specifically catalyzed by human flavin-containing monooxygenase 5.
Drug Metab Dispos
; 39(1): 61-70, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20947616
10.
Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization.
Lab Chip
; 20(3): 446-467, 2020 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31932816
11.
Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C9*3 variants.
Drug Metab Pharmacokinet
; 33(5): 219-227, 2018 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-30219715
12.
Eribulin shows high concentration and long retention in xenograft tumor tissues.
Cancer Chemother Pharmacol
; 80(2): 377-384, 2017 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-28664226
13.
Application of a substrate cocktail approach in the assessment of cytochrome P450 induction using cultured human hepatocytes.
J Biomol Screen
; 18(2): 199-210, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23071008
14.
Synthesis and structure of two new mycolactones isolated from M. ulcerans subsp. shinshuense.
Org Lett
; 14(17): 4618-21, 2012 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22924773
15.
Investigation of the metabolism of rufinamide and its interaction with valproate.
Drug Metab Lett
; 5(4): 280-9, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22022867
16.
In vitro screening of metabolic clearance using two concentration points.
Drug Metab Lett
; 4(4): 233-40, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20690899
17.
High throughput quantitative assessment of CYP inactivation using 2 concentration points.
Drug Metab Lett
; 3(2): 78-82, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19601868