Pesquisa | Secretaria de Estado da Saúde

1.

Revisiting astrocyte to neuron conversion with lineage tracing in vivo.

Wang, Lei-Lei; Serrano, Carolina; Zhong, Xiaoling; Ma, Shuaipeng; Zou, Yuhua; Zhang, Chun-Li.

Cell ; 184(21): 5465-5481.e16, 2021 10 14.

Artigo Inglês | MEDLINE | ID: mdl-34582787

2.

Therapeutic Potential of PTBP1 Inhibition, If Any, Is Not Attributed to Glia-to-Neuron Conversion.

Wang, Lei-Lei; Zhang, Chun-Li.

Annu Rev Neurosci ; 46: 1-15, 2023 07 10.

Artigo Inglês | MEDLINE | ID: mdl-36750409

3.

Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader.

Hu, Xinglin; Huang, Xingwei; Yang, Yue; Sun, Yuchen; Zhao, Yanhua; Zhang, Zhijing; Qiu, Dan; Wu, Yanshuang; Wu, Guangming; Lei, Lei.

Nucleic Acids Res ; 2024 Mar 21.

Artigo Inglês | MEDLINE | ID: mdl-38512058

4.

Epigenetic control of adaptive or homeostatic splicing during interval-training activities.

Liu, Ling; Nguyen, Hai; Das, Urmi; Ogunsola, Samuel; Yu, Jiankun; Lei, Lei; Kung, Matthew; Pejhan, Shervin; Rastegar, Mojgan; Xie, Jiuyong.

Nucleic Acids Res ; 2024 Apr 25.

Artigo Inglês | MEDLINE | ID: mdl-38661216

5.

Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in mice.

Ikami, Kanako; Shoffner-Beck, Suzanne; Tyczynska Weh, Malgorzata; Schnell, Santiago; Yoshida, Shosei; Diaz Miranda, Edgar Andres; Ko, Sooah; Lei, Lei.

Proc Natl Acad Sci U S A ; 120(20): e2219683120, 2023 05 16.

Artigo Inglês | MEDLINE | ID: mdl-37155904

6.

Inflammation and Cholesterol as Predictors of Cardiovascular Events Among 13 970 Contemporary High-Risk Patients With Statin Intolerance.

Ridker, Paul M; Lei, Lei; Louie, Michael J; Haddad, Tariq; Nicholls, Stephen J; Lincoff, A Michael; Libby, Peter; Nissen, Steven E.

Circulation ; 149(1): 28-35, 2024 01 02.

Artigo Inglês | MEDLINE | ID: mdl-37929602

7.

DRONet: effectiveness-driven drug repositioning framework using network embedding and ranking learning.

Yang, Kuo; Yang, Yuxia; Fan, Shuyue; Xia, Jianan; Zheng, Qiguang; Dong, Xin; Liu, Jun; Liu, Qiong; Lei, Lei; Zhang, Yingying; Li, Bing; Gao, Zhuye; Zhang, Runshun; Liu, Baoyan; Wang, Zhong; Zhou, Xuezhong.

Brief Bioinform ; 24(1)2023 01 19.

Artigo Inglês | MEDLINE | ID: mdl-36562715

8.

The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.

Cheng, Qiao; Wang, Dong; Lai, Xiaoxuan; Liu, Yin; Zuo, Yibo; Zhang, Wenli; Lei, Lei; Chen, Jia; Liu, Hong; Wang, Ying; Liu, Haiyan; Zheng, Hui; Wu, Depei; Xu, Yang.

Blood ; 141(12): 1474-1488, 2023 03 23.

Artigo Inglês | MEDLINE | ID: mdl-36574342

9.

A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum.

Zhang, Yunjia; Li, Boxun; Cananzi, Sergio; Han, Chuanhui; Wang, Lei-Lei; Zou, Yuhua; Fu, Yang-Xin; Hon, Gary C; Zhang, Chun-Li.

Proc Natl Acad Sci U S A ; 119(11): e2107339119, 2022 03 15.

Artigo Inglês | MEDLINE | ID: mdl-35254903

10.

Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis.

Dettmer-Monaco, Viviane; Weißert, Kristoffer; Ammann, Sandra; Monaco, Gianni; Lei, Lei; Gräßel, Linda; Rhiel, Manuel; Rositzka, Julia; Kaufmann, Masako M; Geiger, Kerstin; Andrieux, Geoffroy; Lao, Jessica; Thoulass, Gudrun; Schell, Christoph; Boerries, Melanie; Illert, Anna L; Cornu, Tatjana I; Ehl, Stephan; Aichele, Peter; Cathomen, Toni.

J Allergy Clin Immunol ; 153(1): 243-255.e14, 2024 01.

Artigo Inglês | MEDLINE | ID: mdl-37595758

11.

PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation.

Guan, Wen-Liang; Jiang, Lei-Lei; Yin, Xiao-Fang; Hu, Hong-Yu.

J Biol Chem ; 299(8): 105019, 2023 08.

Artigo Inglês | MEDLINE | ID: mdl-37422193

12.

Tinnitus classification based on resting-state functional connectivity using a convolutional neural network architecture.

Xu, Qianhui; Zhou, Lei-Lei; Xing, Chunhua; Xu, Xiaomin; Feng, Yuan; Lv, Han; Zhao, Fei; Chen, Yu-Chen; Cai, Yuexin.

Neuroimage ; 290: 120566, 2024 Apr 15.

Artigo Inglês | MEDLINE | ID: mdl-38467345

13.

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Jiang, Lei-Lei; Guan, Wen-Liang; Wang, Jian-Yang; Zhang, Shu-Xian; Hu, Hong-Yu.

J Cell Sci ; 135(6)2022 03 15.

Artigo Inglês | MEDLINE | ID: mdl-35142363

14.

Palbociclib sensitizes ER-positive breast cancer cells to fulvestrant by promoting the ubiquitin-mediated degradation of ER-α via SNHG17/Hippo-YAP axis.

Lei, Lei; Huang, Yuan; Shi, Lei; Ye, Weiwu; Lv, Xianmei; Ying, Lisha; Yu, Xingfei; Cheng, Skye Hung-Chun; Zheng, Yabing.

Breast Cancer Res Treat ; 203(3): 613-625, 2024 Feb.

Artigo Inglês | MEDLINE | ID: mdl-37924380

15.

Shielding Mn³⁺ Disproportionation with Graphitic Carbon-Interlayered Manganese Oxide Cathodes for Enhanced Aqueous Energy Storage System.

Zhang, Yue; Han, Xu; Huang, Zi-Hang; Lei, Lei; Duan, Xiaoguang; Li, Hui; Ma, Tianyi.

Small ; : e2401849, 2024 Apr 29.

Artigo Inglês | MEDLINE | ID: mdl-38682728

16.

Multiple Treatment of Triple-Negative Breast Cancer Through Gambogic Acid-Loaded Mesoporous Polydopamine.

Liu, Jiaqi; Liu, Hongmei; Huang, Shan; Peng, Hong; Li, Jiamei; Tu, Kerong; Tan, Sumin; Xie, Rou; Lei, Lei; Yue, Qin; Gao, Huile; Cai, Lulu.

Small ; : e2309583, 2024 Mar 06.

Artigo Inglês | MEDLINE | ID: mdl-38446095

17.

DOMAS: a data management software framework for advanced light sources.

Hu, Hao; Lei, Lei; Wang, Haofan; Zhuang, Bo; Zhang, Ruojin; Luo, Qi; Sun, Xiaokang; Qi, Fazhi.

J Synchrotron Radiat ; 31(Pt 2): 312-321, 2024 Mar 01.

Artigo Inglês | MEDLINE | ID: mdl-38300131

18.

Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling.

Wang, Di; Zheng, Mingzhu; Lei, Lei; Ji, Jian; Yao, Yunliang; Qiu, Yuanjun; Ma, Lie; Lou, Jun; Ouyang, Chuan; Zhang, Xue; He, Yuewei; Chi, Jun; Wang, Lie; Kuang, Ying; Wang, Jianli; Cao, Xuetao; Lu, Linrong.

Nat Immunol ; 13(6): 560-8, 2012 May 06.

Artigo Inglês | MEDLINE | ID: mdl-22561606

19.

The molecular characteristics could supplement the staging system of pT2/T3N0M0 esophageal squamous cell carcinoma: a translational study based on a cohort with over 20 years of follow-up.

Jiang, Wen-Mei; Tian, Jia-Yuan; Guo, Yi-Han; Qiu, Li-Hong; Luo, Xing-Yu; Huang, Yang-Yu; Long, Hao; Zhang, Lan-Jun; Lin, Peng; Xu, Xin-Xin; Wu, Lei-Lei; Ma, Guo-Wei.

Cancer Cell Int ; 24(1): 119, 2024 Mar 30.

Artigo Inglês | MEDLINE | ID: mdl-38553712

20.

Non-coding RNAs in diabetic foot ulcer- a focus on infected wounds.

Qin, Boquan; Peng, Qi; Dong, Hongxian; Lei, Lei; Wu, Shizhou.

Diabetes Metab Res Rev ; 40(3): e3740, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-37839046

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