Detalhe da pesquisa
1.
Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance.
Cell
; 185(2): 397-398, 2022 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35063076
2.
A new mechanism of thyroid hormone receptor ß agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles.
Acta Pharmacol Sin
; 2024 May 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38789494
3.
Regulation of the nanostructures self-assembled from an amphiphilic azobenzene homopolymer: influence of initial concentration and solvent solubility parameter.
Soft Matter
; 19(4): 743-748, 2023 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36621933
4.
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.
Cell
; 132(3): 375-86, 2008 Feb 08.
Artigo
Inglês
| MEDLINE | ID: mdl-18267070
5.
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis.
Acta Pharmacol Sin
; 44(8): 1649-1664, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-36997665
6.
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice.
Acta Pharmacol Sin
; 44(3): 596-609, 2023 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-36085523
7.
Efficient Removal of Pb(â ¡) by Highly Porous Polymeric Sponges Self-Assembled from a Poly(Amic Acid).
Molecules
; 28(7)2023 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37049658
8.
Transformation of Amorphous Nanobowls to Crystalline Ellipsoids Induced by Trans-Cis Isomerization of Azobenzene.
Macromol Rapid Commun
; 43(11): e2200131, 2022 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-35322512
9.
Spicatulides A-G, Phenolic-Monoterpenoid Hybrids from Chloranthus spicatus.
J Nat Prod
; 85(8): 2090-2099, 2022 08 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35957573
10.
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.
Clin Sci (Lond)
; 135(19): 2243-2263, 2021 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34569605
11.
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio.
Bioorg Med Chem
; 43: 116280, 2021 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34256254
12.
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice.
Acta Pharmacol Sin
; 42(11): 1834-1846, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33574568
13.
Phytochemicals from the Leaves of Cyclocarya paliurus and their 11ß-HSD1 Enzyme Inhibitory Effects.
Chem Biodivers
; 18(1): e2000772, 2021 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-33369207
14.
Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2.
Acta Pharmacol Sin
; 41(11): 1446-1456, 2020 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-32398684
15.
Risk prediction models for sarcopenia in dialysis patients: a systematic review.
J Ren Nutr
; 2024 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38848803
16.
Structural Elucidation and Bioinspired Total Syntheses of Ascorbylated Diterpenoid Hongkonoids A-D.
J Am Chem Soc
; 140(7): 2485-2492, 2018 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-29394051
17.
Limonoids and Triterpenoids as 11ß-HSD1 Inhibitors from Walsura robusta.
J Nat Prod
; 79(4): 899-906, 2016 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-26936592
18.
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition.
Acta Pharmacol Sin
; 37(10): 1359-1369, 2016 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-27264313
19.
Discovery and Structure-Activity Relationship Study of 4-Phenoxythiazol-5-carboxamides as Highly Potent TGR5 Agonists.
Chem Pharm Bull (Tokyo)
; 64(4): 326-39, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26843013
20.
Yhhu4488, a novel GPR40 agonist, promotes GLP-1 secretion and exerts anti-diabetic effect in rodent models.
Biochem Biophys Res Commun
; 466(4): 740-7, 2015 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26417688