Detalhe da pesquisa
1.
Spousal Influence on Diabetes Self-care: Moderating Effects of Distress and Relationship Quality on Glycemic Control.
Ann Behav Med
; 55(2): 123-132, 2021 03 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32491154
2.
Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.
Bioorg Med Chem Lett
; 40: 127939, 2021 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33713780
3.
Impaired glucose partitioning in primary myotubes from severely obese women with type 2 diabetes.
Am J Physiol Cell Physiol
; 319(6): C1011-C1019, 2020 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32966127
4.
Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits.
J Pharmacol Exp Ther
; 375(3): 510-521, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33033171
5.
Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice.
Am J Physiol Gastrointest Liver Physiol
; 316(5): G653-G667, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30920846
6.
Altered tricarboxylic acid cycle flux in primary myotubes from severely obese humans.
Int J Obes (Lond)
; 43(4): 895-905, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29892037
7.
Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents.
J Pharmacol Exp Ther
; 365(3): 676-687, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29674332
8.
A candidate-gene association study of topiramate-induced weight loss in obese patients with and without type 2 diabetes mellitus.
Pharmacogenet Genomics
; 26(2): 53-65, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26524290
9.
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: part 2. Pyridazine-based analogs.
Bioorg Med Chem Lett
; 24(5): 1437-41, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24405703
10.
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.
Bioorg Med Chem Lett
; 23(24): 6773-6, 2013 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24153205
11.
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome.
PLoS One
; 13(5): e0198156, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29851973
12.
Preclinical developments in type 2 diabetes.
Adv Drug Deliv Rev
; 54(9): 1199-212, 2002 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-12393301
13.
Structure-based design of potent retinoid X receptor alpha agonists.
J Med Chem
; 47(8): 2010-29, 2004 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-15056000
14.
Thioredoxin-mimetic peptide CB3 lowers MAPKinase activity in the Zucker rat brain.
Redox Biol
; 2: 447-56, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24624334
15.
Lipogenic enzymes as therapeutic targets for obesity and diabetes.
Curr Pharm Des
; 17(4): 325-31, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21375498
16.
Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents.
J Med Chem
; 54(3): 788-808, 2011 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-21218783
17.
Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Toxicol Sci
; 117(2): 493-504, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20616206
18.
MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.
Mol Endocrinol
; 23(7): 975-88, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19389808
19.
2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV.
Bioorg Med Chem Lett
; 15(23): 5257-61, 2005 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16168640
20.
Select HIV protease inhibitors alter bone and fat metabolism ex vivo.
J Biol Chem
; 277(22): 19247-50, 2002 May 31.
Artigo
Inglês
| MEDLINE | ID: mdl-11937496