Detalhe da pesquisa
1.
DNA Methylation Inhibitors in Cancer Therapy: The Immunity Dimension.
Cell
; 162(5): 938-9, 2015 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-26317460
2.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Mol Cell
; 81(10): 2183-2200.e13, 2021 05 20.
Artigo
Inglês
| MEDLINE | ID: mdl-34019788
3.
Widespread microRNA degradation elements in target mRNAs can assist the encoded proteins.
Genes Dev
; 35(23-24): 1595-1609, 2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34819352
4.
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Nature
; 589(7841): 299-305, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33299181
5.
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
Blood
; 2024 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38598835
6.
HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
Nucleic Acids Res
; 51(19): 10194-10217, 2023 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37638746
7.
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2.
J Am Chem Soc
; 145(14): 8176-8188, 2023 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36976643
8.
Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma.
Genome Res
; 30(9): 1217-1227, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32820006
9.
Histone mutations in cancer.
Biochem Soc Trans
; 51(5): 1749-1763, 2023 10 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37721138
10.
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.
Immunity
; 38(2): 225-36, 2013 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23415911
11.
Targeting Epigenetics in Cancer.
Annu Rev Pharmacol Toxicol
; 58: 187-207, 2018 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28992434
12.
Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis-Top-Down Mass Spectrometry.
Anal Chem
; 93(12): 5151-5160, 2021 03 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33749242
13.
The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.
Mol Cell
; 51(2): 236-48, 2013 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-23747014
14.
Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.
J Biol Chem
; 294(33): 12459-12471, 2019 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-31248990
15.
USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
Blood
; 132(4): 423-434, 2018 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29844011
16.
Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine.
J Am Soc Nephrol
; 30(8): 1398-1411, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31300484
17.
Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia-reperfusion injury.
Basic Res Cardiol
; 114(2): 7, 2019 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30635790
18.
Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells.
J Biol Chem
; 292(6): 2237-2254, 2017 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28035005
19.
The nucleus is irreversibly shaped by motion of cell boundaries in cancer and non-cancer cells.
J Cell Physiol
; 233(2): 1446-1454, 2018 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-28542912
20.
Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits.
J Cell Biochem
; 119(4): 3267-3279, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29105817