Detalhe da pesquisa
1.
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19.
J Mol Cell Cardiol
; 167: 92-96, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35339512
2.
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation.
Immunity
; 38(2): 285-95, 2013 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23395675
3.
Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention.
J Interv Cardiol
; 2022: 9154048, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36262459
4.
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Br J Clin Pharmacol
; 88(12): 5295-5306, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35748053
5.
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.
Pharmacol Rev
; 71(4): 467-502, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31492821
6.
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction.
Eur Heart J
; 41(34): 3239-3252, 2020 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31972008
8.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Circulation
; 135(12): 1160-1173, 2017 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-28137936
9.
Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes.
J Mol Cell Cardiol
; 147: 88-91, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32818486
10.
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
Front Pharmacol
; 15: 1369489, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38655187
11.
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Biosci Rep
; 2024 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38747277
12.
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.
Nat Med
; 12(9): 1075-80, 2006 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16892061
13.
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function.
Pharmacol Rev
; 62(4): 565-78, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21079036
14.
International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function.
Pharmacol Rev
; 62(3): 331-42, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20605969
15.
Targeting the apelin system for the treatment of cardiovascular diseases.
Cardiovasc Res
; 119(17): 2683-2696, 2023 12 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37956047
16.
Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands.
Front Endocrinol (Lausanne)
; 14: 1139121, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36967803
17.
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes.
Cardiovasc Res
; 119(2): 587-598, 2023 03 31.
Artigo
Inglês
| MEDLINE | ID: mdl-36239923
18.
International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.
Pharmacol Rev
; 61(1): 1-8, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19325074
19.
The therapeutic potential of apelin in kidney disease.
Nat Rev Nephrol
; 17(12): 840-853, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34389827
20.
In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide quantification in tissues by ELISA.
Peptides
; 145: 170642, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34455010