Detalhe da pesquisa
1.
ChemFOnt: the chemical functional ontology resource.
Nucleic Acids Res
; 51(D1): D1220-D1229, 2023 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36305829
2.
HMDB 5.0: the Human Metabolome Database for 2022.
Nucleic Acids Res
; 50(D1): D622-D631, 2022 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34986597
3.
NP-MRD: the Natural Products Magnetic Resonance Database.
Nucleic Acids Res
; 50(D1): D665-D677, 2022 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34791429
4.
In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor.
Bioorg Med Chem Lett
; 28(20): 3404-3408, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30217415
5.
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument.
Bioorg Med Chem Lett
; 26(19): 4837-4841, 2016 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27542305
6.
Discovery of a novel tricyclic 4H-thiazolo[5',4':4,5]pyrano[2,3-c]pyridine-2-amino scaffold and its application in a PI3Kα inhibitor with high PI3K isoform selectivity and potent cellular activity.
Bioorg Med Chem Lett
; 25(17): 3582-4, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26164189
7.
Identification and optimisation of 4,5-dihydrobenzo[1,2-d:3,4-d]bisthiazole and 4,5-dihydrothiazolo[4,5-h]quinazoline series of selective phosphatidylinositol-3 kinase alpha inhibitors.
Bioorg Med Chem Lett
; 25(17): 3575-81, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26199119
8.
Drug discovery considerations in the development of covalent inhibitors.
Bioorg Med Chem Lett
; 24(1): 33-9, 2014 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24314671
9.
Correction to "2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4".
ACS Med Chem Lett
; 11(11): 2341, 2020 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33214851
10.
Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.
J Med Chem
; 63(21): 12542-12573, 2020 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32930584
11.
The P1N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin.
Bioorg Med Chem Lett
; 19(16): 4863-7, 2009 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19615901
12.
Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes.
ChemMedChem
; 14(14): 1305-1314, 2019 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31066983
13.
FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer.
Mol Cancer Ther
; 18(12): 2194-2206, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31409633
14.
2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4.
ACS Med Chem Lett
; 9(3): 215-220, 2018 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29541363
15.
Hypovitaminosis D correction and high-sensitivity C-reactive protein levels in hypertensive adults.
Perm J
; 17(4): 19-21, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24361015
16.
The NASA Smart Probe Project for real-time multiple microsensor tissue recognition.
Stereotact Funct Neurosurg
; 80(1-4): 114-9, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-14745219
17.
Biphenyl derivatives as novel dual NK(1)/NK(2)-receptor antagonists.
Bioorg Med Chem Lett
; 12(16): 2065-8, 2002 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-12127505
18.
Structure-based design of aliskiren, a novel orally effective renin inhibitor.
Biochem Biophys Res Commun
; 308(4): 698-705, 2003 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-12927775
19.
Real-time multiple microsensor tissue recognition and its potential application in the management of prostate cancer.
BJU Int
; 97(2): 222-3, 2006 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-16430616
20.
The future role of intelligent probes in detecting and managing prostate cancer.
BJU Int
; 98(4): 717-9, 2006 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16978262