Pesquisa | Secretaria de Estado da Saúde

1.

RNA-methylation-dependent RNA processing controls the speed of the circadian clock.

Fustin, Jean-Michel; Doi, Masao; Yamaguchi, Yoshiaki; Hida, Hayashi; Nishimura, Shinichi; Yoshida, Minoru; Isagawa, Takayuki; Morioka, Masaki Suimye; Kakeya, Hideaki; Manabe, Ichiro; Okamura, Hitoshi.

Cell ; 155(4): 793-806, 2013 Nov 07.

Artigo Inglês | MEDLINE | ID: mdl-24209618

2.

Identification of a KLF5-dependent program and drug development for skeletal muscle atrophy.

Liu, Lin; Koike, Hiroyuki; Ono, Takehito; Hayashi, Shinichiro; Kudo, Fujimi; Kaneda, Atsushi; Kagechika, Hiroyuki; Manabe, Ichiro; Nakashima, Tomoki; Oishi, Yumiko.

Proc Natl Acad Sci U S A ; 118(35)2021 08 31.

Artigo Inglês | MEDLINE | ID: mdl-34426497

3.

Nerve-macrophage interactions in cardiovascular disease.

Fujiu, Katsuhito; Manabe, Ichiro.

Int Immunol ; 34(2): 81-95, 2022 01 22.

Artigo Inglês | MEDLINE | ID: mdl-34173833

4.

A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation.

Nakayama, Yukiteru; Fujiu, Katsuhito; Yuki, Ryuzaburo; Oishi, Yumiko; Morioka, Masaki Suimye; Isagawa, Takayuki; Matsuda, Jun; Oshima, Tsukasa; Matsubara, Takumi; Sugita, Junichi; Kudo, Fujimi; Kaneda, Atsushi; Endo, Yusuke; Nakayama, Toshinori; Nagai, Ryozo; Komuro, Issei; Manabe, Ichiro.

Proc Natl Acad Sci U S A ; 117(25): 14365-14375, 2020 06 23.

Artigo Inglês | MEDLINE | ID: mdl-32513690

5.

p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells.

Nagano, Hidekazu; Hashimoto, Naoko; Nakayama, Akitoshi; Suzuki, Sawako; Miyabayashi, Yui; Yamato, Azusa; Higuchi, Seiichiro; Fujimoto, Masanori; Sakuma, Ikki; Beppu, Minako; Yokoyama, Masataka; Suzuki, Yutaka; Sugano, Sumio; Ikeda, Kazuhiro; Tatsuno, Ichiro; Manabe, Ichiro; Yokote, Koutaro; Inoue, Satoshi; Tanaka, Tomoaki.

Proc Natl Acad Sci U S A ; 115(33): 8370-8375, 2018 08 14.

Artigo Inglês | MEDLINE | ID: mdl-30061407

6.

Two Ck1Î´ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.

Fustin, Jean-Michel; Kojima, Rika; Itoh, Kakeru; Chang, Hsin-Yi; Ye, Shiqi; Zhuang, Bowen; Oji, Asami; Gibo, Shingo; Narasimamurthy, Rajesh; Virshup, David; Kurosawa, Gen; Doi, Masao; Manabe, Ichiro; Ishihama, Yasushi; Ikawa, Masahito; Okamura, Hitoshi.

Proc Natl Acad Sci U S A ; 115(23): 5980-5985, 2018 06 05.

Artigo Inglês | MEDLINE | ID: mdl-29784786

7.

Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4.

Azami, Takuya; Waku, Tsuyoshi; Matsumoto, Ken; Jeon, Hyojung; Muratani, Masafumi; Kawashima, Akihiro; Yanagisawa, Jun; Manabe, Ichiro; Nagai, Ryozo; Kunath, Tilo; Nakamura, Tomonori; Kurimoto, Kazuki; Saitou, Mitinori; Takahashi, Satoru; Ema, Masatsugu.

Development ; 144(20): 3706-3718, 2017 10 15.

Artigo Inglês | MEDLINE | ID: mdl-28870993

8.

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.

Tara, Shiro; Isshiki, Yusuke; Nakajima-Takagi, Yaeko; Oshima, Motohiko; Aoyama, Kazumasa; Tanaka, Tomoyuki; Shinoda, Daisuke; Koide, Shuhei; Saraya, Atsunori; Miyagi, Satoru; Manabe, Ichiro; Matsui, Hirotaka; Koseki, Haruhiko; Bardwell, Vivian J; Iwama, Atsushi.

Blood ; 132(23): 2470-2483, 2018 12 06.

Artigo Inglês | MEDLINE | ID: mdl-30228234

9.

Signaling Pathways Potentially Responsible for Foam Cell Formation: Cholesterol Accumulation or Inflammatory Response-What is First?

Orekhov, Alexander N; Sukhorukov, Vasily N; Nikiforov, Nikita G; Kubekina, Marina V; Sobenin, Igor A; Foxx, Kathy K; Pintus, Sergey; Stegmaier, Philip; Stelmashenko, Daria; Kel, Alexander; Poznyak, Anastasia V; Wu, Wei-Kai; Kasianov, Artem S; Makeev, Vsevolod Y; Manabe, Ichiro; Oishi, Yumiko.

Int J Mol Sci ; 21(8)2020 Apr 14.

Artigo Inglês | MEDLINE | ID: mdl-32295185

10.

Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis.

Orekhov, Alexander N; Nikiforov, Nikita G; Sukhorukov, Vasily N; Kubekina, Marina V; Sobenin, Igor A; Wu, Wei-Kai; Foxx, Kathy K; Pintus, Sergey; Stegmaier, Philip; Stelmashenko, Daria; Kel, Alexander; Gratchev, Alexei N; Melnichenko, Alexandra A; Wetzker, Reinhard; Summerhill, Volha I; Manabe, Ichiro; Oishi, Yumiko.

Int J Mol Sci ; 21(3)2020 Jan 27.

Artigo Inglês | MEDLINE | ID: mdl-32012706

11.

Macrophages in inflammation, repair and regeneration.

Oishi, Yumiko; Manabe, Ichiro.

Int Immunol ; 30(11): 511-528, 2018 10 29.

Artigo Inglês | MEDLINE | ID: mdl-30165385

12.

Therapeutic targeting of mitochondrial ROS ameliorates murine model of volume overload cardiomyopathy.

Okamura, Kenichi; Nakagama, Yu; Takeda, Norihiko; Soma, Katsura; Sato, Tatsuyuki; Isagawa, Takayuki; Kido, Yasutoshi; Sakamoto, Masaya; Manabe, Ichiro; Hirata, Yasutaka; Komuro, Issei; Ono, Minoru.

J Pharmacol Sci ; 141(1): 56-63, 2019 Sep.

Artigo Inglês | MEDLINE | ID: mdl-31611176

13.

Murine Model of Pulmonary Artery Overflow Vasculopathy Revealed Macrophage Accumulation in the Lung.

Minatsuki, Shun; Takeda, Norihiko; Soma, Katsura; Katoh, Manami; Maki, Hisataka; Hatano, Masaru; Takimoto, Eiki; Manabe, Ichiro; Komuro, Issei.

Int Heart J ; 60(2): 451-456, 2019 Mar 20.

Artigo Inglês | MEDLINE | ID: mdl-30799373

14.

Cell Cycle Perturbation Induces Collagen Production in Fibroblasts.

Wake, Masaki; Takeda, Norihiko; Isagawa, Takayuki; Sato, Tatsuyuki; Nakagama, Yu; Morioka, Masaki Suimye; Hirota, Yasushi; Asagiri, Masataka; Maemura, Koji; Manabe, Ichiro; Tanabe, Kazuaki; Komuro, Issei.

Int Heart J ; 60(4): 958-963, 2019 Jul 27.

Artigo Inglês | MEDLINE | ID: mdl-31308330

15.

CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.

Suzuki, Shinnosuke; Nozawa, Yusuke; Tsukamoto, Satoshi; Kaneko, Takehito; Manabe, Ichiro; Imai, Hiroshi; Minami, Naojiro.

Development ; 142(13): 2375-84, 2015 Jul 01.

Artigo Inglês | MEDLINE | ID: mdl-26092847

16.

Noninvasive screening test for detecting early stage lymphedema using follow-up computed tomography imaging after cancer treatment and results of treatment with lymphaticovenular anastomosis.

Akita, Shinsuke; Ogata, Fusa; Manabe, Ichiro; Mitsuhashi, Akira; Nakamura, Rikiya; Yamaji, Yoshihisa; Kubota, Yoshitaka; Mitsukawa, Nobuyuki.

Microsurgery ; 37(8): 910-916, 2017 Nov.

Artigo Inglês | MEDLINE | ID: mdl-28621805

17.

[Adipose stem cell system.]

Oishi, Yumiko; Manabe, Ichiro.

Clin Calcium ; 27(6): 795-801, 2017.

Artigo Japonês | MEDLINE | ID: mdl-28536316

18.

Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice.

Motokawa, Ikuyo; Endo, Motoyoshi; Terada, Kazutoyo; Horiguchi, Haruki; Miyata, Keishi; Kadomatsu, Tsuyoshi; Morinaga, Jun; Sugizaki, Taichi; Ito, Takaaki; Araki, Kimi; Morioka, Masaki Suimye; Manabe, Ichiro; Samukawa, Takuya; Watanabe, Masaki; Inoue, Hiromasa; Oike, Yuichi.

Am J Physiol Lung Cell Mol Physiol ; 311(4): L704-L713, 2016 Oct 01.

Artigo Inglês | MEDLINE | ID: mdl-27542805

19.

Integrated regulation of the cellular metabolism and function of immune cells in adipose tissue.

Oishi, Yumiko; Manabe, Ichiro.

Clin Exp Pharmacol Physiol ; 43(3): 294-303, 2016 Mar.

Artigo Inglês | MEDLINE | ID: mdl-26728525

20.

Inflammaging.

Oishi, Yumiko; Manabe, Ichiro.

Nihon Rinsho ; 74(9): 1441-1445, 2016 Sep.

Artigo Japonês | MEDLINE | ID: mdl-30557474

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RNA-methylation-dependent RNA processing controls the speed of the circadian clock.

Identification of a KLF5-dependent program and drug development for skeletal muscle atrophy.

Nerve-macrophage interactions in cardiovascular disease.

A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation.

p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells.

Two Ck1Î´ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.

Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4.

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.

Signaling Pathways Potentially Responsible for Foam Cell Formation: Cholesterol Accumulation or Inflammatory Response-What is First?

Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis.

Macrophages in inflammation, repair and regeneration.

Therapeutic targeting of mitochondrial ROS ameliorates murine model of volume overload cardiomyopathy.

Murine Model of Pulmonary Artery Overflow Vasculopathy Revealed Macrophage Accumulation in the Lung.

Cell Cycle Perturbation Induces Collagen Production in Fibroblasts.

CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.

Noninvasive screening test for detecting early stage lymphedema using follow-up computed tomography imaging after cancer treatment and results of treatment with lymphaticovenular anastomosis.

[Adipose stem cell system.]

Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice.

Integrated regulation of the cellular metabolism and function of immune cells in adipose tissue.

Inflammaging.