Detalhe da pesquisa
1.
Early postnatal oleic acid administration enhances synaptic development and cognitive abilities in the Ts65Dn mouse model of Down syndrome.
Nutr Neurosci
; 25(7): 1400-1412, 2022 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-33345728
2.
Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies.
Int J Mol Sci
; 22(3)2021 Jan 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33514010
3.
Prenatal, but not Postnatal, Curcumin Administration Rescues Neuromorphological and Cognitive Alterations in Ts65Dn Down Syndrome Mice.
J Nutr
; 150(9): 2478-2489, 2020 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32729926
4.
Prenatal Administration of Oleic Acid or Linolenic Acid Reduces Neuromorphological and Cognitive Alterations in Ts65dn Down Syndrome Mice.
J Nutr
; 150(6): 1631-1643, 2020 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32243527
5.
Signalling Pathways Implicated in Alzheimer's Disease Neurodegeneration in Individuals with and without Down Syndrome.
Int J Mol Sci
; 21(18)2020 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32962300
6.
Cerebellar alterations in a model of Down syndrome: The role of the Dyrk1A gene.
Neurobiol Dis
; 110: 206-217, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29221819
7.
Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice.
Brain Behav Immun
; 73: 235-251, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29758264
8.
Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Neurobiol Dis
; 106: 76-88, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28647555
9.
New Perspectives for the Rescue of Cognitive Disability in Down Syndrome.
J Neurosci
; 35(41): 13843-52, 2015 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26468184
10.
The relationship between behavior acquisition and persistence abilities: Involvement of adult hippocampal neurogenesis.
Hippocampus
; 26(7): 857-74, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26788800
11.
Chronic Melatonin Administration Reduced Oxidative Damage and Cellular Senescence in the Hippocampus of a Mouse Model of Down Syndrome.
Neurochem Res
; 41(11): 2904-2913, 2016 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-27450081
12.
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Hum Mol Genet
; 22(14): 2775-84, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23512985
13.
Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.
J Neurosci
; 33(9): 3953-66, 2013 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-23447605
14.
Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.
J Pineal Res
; 56(1): 51-61, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24147912
15.
Apoptosis in Down's syndrome: lessons from studies of human and mouse models.
Apoptosis
; 18(2): 121-34, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23224708
16.
Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome.
J Pineal Res
; 54(3): 346-58, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23350971
17.
Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities.
Neural Plast
; 2012: 584071, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22685678
18.
Fatty Acids: A Safe Tool for Improving Neurodevelopmental Alterations in Down Syndrome?
Nutrients
; 14(14)2022 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35889838
19.
Oxidative-Stress-Associated Proteostasis Disturbances and Increased DNA Damage in the Hippocampal Granule Cells of the Ts65Dn Model of Down Syndrome.
Antioxidants (Basel)
; 11(12)2022 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36552646
20.
Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer's Disease.
Front Pharmacol
; 12: 613211, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33935706