Detalhe da pesquisa
1.
Sensing and reacting to microbes through the inflammasomes.
Nat Immunol
; 13(4): 325-32, 2012 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-22430785
2.
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.
Immunity
; 43(5): 923-32, 2015 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26572062
3.
Distinct Commensals Induce Interleukin-1ß via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury.
Immunity
; 42(4): 744-55, 2015 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25862092
4.
Interleukin-22 regulates the complement system to promote resistance against pathobionts after pathogen-induced intestinal damage.
Immunity
; 41(4): 620-32, 2014 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25367575
5.
K⺠efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Immunity
; 38(6): 1142-53, 2013 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-23809161
6.
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.
Nat Immunol
; 10(3): 241-7, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19221555
7.
Staphylococcus δ-toxin induces allergic skin disease by activating mast cells.
Nature
; 503(7476): 397-401, 2013 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-24172897
8.
Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.
PLoS Pathog
; 10(2): e1003926, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24516390
9.
Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux.
J Immunol
; 193(8): 4214-4222, 2014 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25225670
10.
3,4-methylenedioxy-ß-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.
J Biol Chem
; 289(2): 1142-50, 2014 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24265316
11.
Bacterial RNA mediates activation of caspase-1 and IL-1ß release independently of TLRs 3, 7, 9 and TRIF but is dependent on UNC93B.
J Immunol
; 189(1): 328-36, 2012 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22634614
12.
Inflammasomes as microbial sensors.
Eur J Immunol
; 40(3): 611-5, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20201013
13.
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome.
J Immunol
; 183(6): 3942-8, 2009 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19717510
14.
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.
J Immunol
; 183(9): 5823-9, 2009 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19812205
15.
A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells.
J Immunol Methods
; 447: 1-13, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28268194
16.
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Nat Med
; 21(3): 248-55, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25686105
17.
In vivo mapping of a protective linear neutralizing epitope at the N-terminus of alpha hemolysin from Staphylococcus aureus.
Mol Immunol
; 60(1): 62-71, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24769493
18.
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation.
J Immunol
; 178(12): 8022-7, 2007 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17548639