Detalhe da pesquisa
1.
An inherited life-threatening arrhythmia model established by screening randomly mutagenized mice.
Proc Natl Acad Sci U S A
; 121(17): e2218204121, 2024 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38621141
2.
Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc Natl Acad Sci U S A
; 119(30): e2122140119, 2022 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35867837
3.
Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating.
Proc Natl Acad Sci U S A
; 119(32): e2201286119, 2022 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35925888
4.
Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor.
Chem Pharm Bull (Tokyo)
; 72(4): 399-407, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38644198
5.
Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring.
Mol Pharmacol
; 104(6): 275-286, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37678938
6.
Differential effects of the formin inhibitor SMIFH2 on contractility and Ca2+ handling in frog and mouse cardiomyocytes.
Genes Cells
; 26(8): 583-595, 2021 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-34060165
7.
Structural basis for diamide modulation of ryanodine receptor.
Nat Chem Biol
; 16(11): 1246-1254, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32807966
8.
TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle.
Circ Res
; 126(4): 417-435, 2020 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31805819
9.
Loss-of-function mutations in cardiac ryanodine receptor channel cause various types of arrhythmias including long QT syndrome.
Europace
; 24(3): 497-510, 2022 03 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34661651
10.
Development of a water-soluble ryanodine receptor 1 inhibitor.
Bioorg Med Chem
; 74: 117027, 2022 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36223685
11.
Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies.
J Muscle Res Cell Motil
; 42(2): 291-304, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32040690
12.
Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation.
J Electrocardiol
; 69: 111-118, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34656916
13.
The Ryanodine Receptor as a Sensor for Intracellular Environments in Muscles.
Int J Mol Sci
; 22(19)2021 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34639137
14.
Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a Ryanodine Receptor Type 2 Missense Mutation.
Circ J
; 84(2): 226-234, 2020 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31875585
15.
Effects of intravesicular loading of a Ca2+ chelator and depolymerization of actin fibers on neurotransmitter release in frog motor nerve terminals.
Eur J Neurosci
; 50(1): 1700-1711, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30687962
16.
Conversion of Ca2+ oscillation into propagative electrical signals by Ca2+-activated ion channels and connexin as a reconstituted Ca2+ clock model for the pacemaker activity.
Biochem Biophys Res Commun
; 510(2): 242-247, 2019 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30686532
17.
Efficient High-Throughput Screening by Endoplasmic Reticulum Ca2+ Measurement to Identify Inhibitors of Ryanodine Receptor Ca2+-Release Channels.
Mol Pharmacol
; 94(1): 722-730, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29674523
18.
Changes in serum interleukin-6 levels as possible predictor of efficacy of tocilizumab treatment in rheumatoid arthritis.
Mod Rheumatol
; 28(4): 592-598, 2018 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-28880691
19.
[Rapid exacerbation of thrombotic microangiopathy accompanied by electrocardiogram abnormality leading to death].
Rinsho Ketsueki
; 59(7): 895-898, 2018.
Artigo
Japonês
| MEDLINE | ID: mdl-30078800
20.
Therapeutic potential of ghrelin and des-acyl ghrelin against chemotherapy-induced cardiotoxicity.
Endocr J
; 64(Suppl.): S35-S39, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28652542