Detalhe da pesquisa
1.
Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody Distribution.
AAPS J
; 26(2): 33, 2024 03 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38478197
2.
Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure.
Front Oncol
; 14: 1346502, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38577337
3.
High ionic strength dissociation assay reduces dimeric target interference in immunogenicity testing.
Bioanalysis
; 15(14): 823-832, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37326333
4.
Enhanced immunogenic potential of cancer immunotherapy antibodies in human IgG1 transgenic mice.
MAbs
; 14(1): 2143009, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36394299
5.
The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance.
MAbs
; 13(1): 1995929, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34763611