Detalhe da pesquisa
1.
Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Proc Natl Acad Sci U S A
; 120(28): e2302485120, 2023 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37399416
2.
Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
Genes Dev
; 31(18): 1847-1857, 2017 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29021240
3.
Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity.
J Biol Chem
; 299(8): 104917, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37315788
4.
Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia.
BMC Cancer
; 24(1): 414, 2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38570770
5.
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Genes Dev
; 30(17): 1943-55, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27633013
6.
Pubertal exposure to dietary advanced glycation end products disrupts ductal morphogenesis and induces atypical hyperplasia in the mammary gland.
Breast Cancer Res
; 25(1): 118, 2023 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37803429
7.
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Genes Dev
; 29(16): 1707-20, 2015 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26302789
8.
The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Breast Cancer Res
; 23(1): 65, 2021 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34118960
9.
Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.
J Immunol
; 200(6): 2209-2223, 2018 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29440354
10.
IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-κB.
J Immunol
; 199(7): 2333-2342, 2017 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28842466
11.
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Gut
; 67(2): 320-332, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27797936
12.
MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
Mol Cell
; 37(5): 620-32, 2010 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-20227367
13.
FGFR and PTEN signaling interact during lens development to regulate cell survival.
Dev Biol
; 410(2): 150-163, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26764128
14.
Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.
J Cell Physiol
; 231(3): 630-40, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26218069
15.
The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).
J Biol Chem
; 289(1): 326-34, 2014 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24257758
16.
Inhibitor κB kinase 2 is a myosin light chain kinase in vascular smooth muscle.
Circ Res
; 113(5): 562-70, 2013 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-23817200
17.
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Nature
; 461(7267): 1084-91, 2009 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-19847259
18.
Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
Nature
; 451(7174): 73-5, 2008 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-18172498
19.
Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.
Mol Ther
; 21(8): 1517-25, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23732993
20.
NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis.
J Immunol
; 187(5): 2740-7, 2011 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21775686