Detalhe da pesquisa
1.
Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2.
EMBO Rep
; 24(12): e57424, 2023 Dec 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37860832
2.
Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2.
J Clin Immunol
; 43(4): 808-818, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36753016
3.
Human intracellular ISG15 prevents interferon-α/ß over-amplification and auto-inflammation.
Nature
; 517(7532): 89-93, 2015 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25307056
4.
Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent.
J Immunol
; 190(5): 2335-44, 2013 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23359498
5.
Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4⺠T cells.
Eur J Immunol
; 43(10): 2730-40, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23839924
6.
USP18 establishes the transcriptional and anti-proliferative interferon α/ß differential.
Biochem J
; 446(3): 509-16, 2012 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22731491
7.
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense.
PLoS Genet
; 5(7): e1000562, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19609346
8.
IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation.
Front Immunol
; 13: 939907, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35935998
9.
A partial form of inherited human USP18 deficiency underlies infection and inflammation.
J Exp Med
; 219(4)2022 04 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35258551
10.
A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes.
J Exp Med
; 219(6)2022 06 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35442418
11.
Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family.
Hum Mutat
; 32(6): 643-52, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21618349
12.
Genome-Wide Gene Expression Analysis of Mtb-Infected DC Highlights the Rapamycin-Driven Modulation of Regulatory Cytokines via the mTOR/GSK-3ß Axis.
Front Immunol
; 12: 649475, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33936070
13.
Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon ß Treatment.
Front Immunol
; 12: 628375, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34113337
14.
Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency.
J Clin Invest
; 131(1)2021 01 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32960813
15.
Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes.
J Immunol
; 181(9): 5847-56, 2008 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18941173
16.
Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage.
PLoS One
; 15(1): e0225289, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-31961910
17.
Human Ubiquitin-Specific Peptidase 18 Is Regulated by microRNAs via the 3'Untranslated Region, A Sequence Duplicated in Long Intergenic Non-coding RNA Genes Residing in chr22q11.21.
Front Genet
; 11: 627007, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33633774
18.
COPZ1 depletion in thyroid tumor cells triggers type I IFN response and immunogenic cell death.
Cancer Lett
; 476: 106-119, 2020 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32061953
19.
USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression.
Sci Rep
; 9(1): 4066, 2019 03 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30858391
20.
Ligand-independent pathway that controls stability of interferon alpha receptor.
Biochem Biophys Res Commun
; 367(2): 388-93, 2008 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-18166147