Detalhe da pesquisa
1.
Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough.
PLoS Biol
; 19(5): e3001221, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33939688
2.
Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903.
J Biol Chem
; 298(2): 101546, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34999117
3.
Effect of small molecule eRF3 degraders on premature termination codon readthrough.
Nucleic Acids Res
; 49(7): 3692-3708, 2021 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33764477
4.
Biophysical characterization of the ETV6 PNT domain polymerization interfaces.
J Biol Chem
; 296: 100284, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33450226
5.
Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation.
J Virol
; 95(11)2021 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33762409
6.
Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening.
Biochem J
; 476(3): 499-512, 2019 02 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30622151
7.
Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity.
Proc Natl Acad Sci U S A
; 114(13): 3479-3484, 2017 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28289221
8.
Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus.
Molecules
; 25(12)2020 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32599753
9.
Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.
Nucleic Acids Res
; 44(14): 6583-98, 2016 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27407112
10.
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.
PLoS Pathog
; 8(5): e1002691, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22589723
11.
The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility.
Exp Cell Res
; 319(6): 908-17, 2013 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23333560
12.
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.
J Biol Chem
; 287(21): 17530-17545, 2012 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-22474287
13.
Synthesis and biological studies of neopetrosiamides as inhibitors of cancer cell invasion.
Org Biomol Chem
; 11(9): 1476-81, 2013 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23334605
14.
Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA.
Nanomedicine
; 9(5): 665-74, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23219877
15.
Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin.
J Biol Chem
; 286(9): 7290-300, 2011 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21193398
16.
Cell cycle arrest through inhibition of tubulin polymerization by withaphysalin F, a bioactive compound isolated from Acnistus arborescens.
Invest New Drugs
; 30(3): 959-66, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21416228
17.
Hortonones A to C, hydroazulenones from the genus Hortonia.
J Nat Prod
; 75(6): 1189-91, 2012 Jun 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22626446
18.
NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough.
iScience
; 25(3): 103891, 2022 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35243249
19.
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.
Cell Chem Biol
; 29(5): 870-882.e11, 2022 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34520745
20.
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.
Antimicrob Agents Chemother
; 55(8): 3861-9, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21576426