Detalhe da pesquisa
1.
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell
; 173(3): 706-719.e13, 2018 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29677514
2.
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion.
EMBO J
; 42(14): e113168, 2023 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37248947
3.
The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol Cell
; 73(3): 490-504.e6, 2019 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30581145
4.
G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes.
Nucleic Acids Res
; 52(5): 2290-2305, 2024 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38113270
5.
Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot-Marie-Tooth type 2A.
Cell Mol Life Sci
; 80(12): 373, 2023 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38007410
6.
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Brain Behav Immun
; 114: 414-429, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37716378
7.
Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aß clearance while preserving synapses.
Cell Mol Life Sci
; 79(8): 453, 2022 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-35895133
8.
The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation.
Nucleic Acids Res
; 49(13): 7713-7731, 2021 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34233002
9.
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Nucleic Acids Res
; 48(12): 6889-6905, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32479602
10.
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
EMBO J
; 35(14): 1504-21, 2016 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27252488
11.
FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors.
Nucleic Acids Res
; 43(20): 9711-28, 2015 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26250115
12.
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
Acta Neuropathol
; 131(4): 587-604, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26895297
13.
Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
RNA
; 19(10): 1432-48, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23962664
14.
Synthesis and characterization of photoaffinity probes that target the 5-HT3 receptor.
Chimia (Aarau)
; 68(4): 239-42, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24983606
15.
Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
Stem Cell Reports
; 19(2): 187-195, 2024 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38242131
16.
Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun
; 14(1): 5366, 2023 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37666821
17.
Mimicking hypomethylation of FUS requires liquid-liquid phase separation to induce synaptic dysfunctions.
Acta Neuropathol Commun
; 11(1): 199, 2023 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38105257
18.
The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.
Nucleic Acids Res
; 38(21): 7637-50, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20634199
19.
Alternative Splicing in Human Biology and Disease.
Methods Mol Biol
; 2537: 1-19, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35895255
20.
Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation.
Hum Mol Genet
; 18(3): 546-55, 2009 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19010792