Detalhe da pesquisa
1.
Target-Specific Precision of CRISPR-Mediated Genome Editing.
Mol Cell
; 73(4): 699-713.e6, 2019 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30554945
2.
Redistribution of EZH2 promotes malignant phenotypes by rewiring developmental programmes.
EMBO Rep
; 20(10): e48155, 2019 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31468686
3.
Label-Free Mass Spectrometry-Based Quantification of Linker Histone H1 Variants in Clinical Samples.
Int J Mol Sci
; 21(19)2020 Oct 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33020374
4.
Histone H1 alterations in cancer.
Biochim Biophys Acta
; 1859(3): 533-9, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26386351
5.
Cancer Evolution: A Multifaceted Affair.
Cancer Discov
; 14(1): 36-48, 2024 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38047596
6.
CRISPR-based large-scale modeling of loss-of-function mutations to investigate mechanisms of stress resistance in cancer.
STAR Protoc
; 4(1): 102097, 2023 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36853711
7.
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia.
Cancer Cell
; 41(1): 70-87.e14, 2023 01 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36332625
8.
H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function.
Nat Struct Mol Biol
; 30(7): 935-947, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37308596
9.
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome.
Nat Med
; 11(4): 440-5, 2005 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-15750600
10.
Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability.
Nat Cell Biol
; 23(4): 401-412, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33837287
11.
ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer.
Oncogene
; 40(16): 2923-2935, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33742126
12.
Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis.
Nat Commun
; 11(1): 1792, 2020 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32286289
13.
Good news in the nuclear envelope: loss of lamin A might be a gain.
J Clin Invest
; 116(3): 632-4, 2006 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16511598
14.
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.
Nat Commun
; 10(1): 3101, 2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31308377
15.
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins.
Mol Cell Biol
; 24(14): 6393-402, 2004 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-15226439
16.
Genome instability in progeria: when repair gets old.
Nat Med
; 11(7): 718-9, 2005 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16015360
17.
Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.
Mol Biol Cell
; 14(8): 3414-26, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12925773
18.
Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to in vivo assays.
Epigenetics
; 12(12): 1065-1075, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-29327641
19.
Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity.
Trends Cancer
; 3(5): 372-386, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28718414
20.
The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity.
Science
; 353(6307)2016 09 30.
Artigo
Inglês
| MEDLINE | ID: mdl-27708074