Detalhe da pesquisa
1.
Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
J Biol Chem
; 295(10): 3115-3133, 2020 03 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32005658
2.
Small-molecule control of antibody N-glycosylation in engineered mammalian cells.
Nat Chem Biol
; 15(7): 730-736, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31110306
3.
The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1.
Genes Dev
; 25(10): 1052-64, 2011 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21576265
4.
Reactivity-driven cleanup of 2-Aminobenzamide derivatized oligosaccharides.
Anal Biochem
; 546: 23-27, 2018 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29407581
5.
A high-fidelity, dual site-specific integration system in CHO cells by a Bxb1 recombinase.
Biotechnol J
; 19(2): e2300410, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38375559
6.
Transport of messenger RNA from the nucleus to the cytoplasm.
Curr Opin Cell Biol
; 18(3): 299-306, 2006 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-16682182
7.
A genetic off-target event in a site-specific integration cell line expressing monoclonal antibody has no impact on commercial suitability.
Biotechnol Prog
; 39(2): e3320, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36545889
8.
The impact of expression vector position on transgene transcription allows for rational expression vector design in a targeted integration system.
Biotechnol J
; 18(9): e2300038, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37272404
9.
Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum.
J Cell Sci
; 123(Pt 1): 141-51, 2010 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20016074
10.
The yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes.
J Cell Biol
; 178(5): 799-812, 2007 Aug 27.
Artigo
Inglês
| MEDLINE | ID: mdl-17724120
11.
Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase.
FEMS Yeast Res
; 12(3): 305-16, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22151002
12.
New Opportunities in Glycan Engineering for Therapeutic Proteins.
Antibodies (Basel)
; 11(1)2022 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35076453
13.
Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation.
J Biotechnol
; 360: 79-91, 2022 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36341973
14.
Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule.
Biotechnol Prog
; 37(4): e3158, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33891804
15.
Synthetic genetic array analysis in Saccharomyces cerevisiae provides evidence for an interaction between RAT8/DBP5 and genes encoding P-body components.
Genetics
; 179(4): 1945-55, 2008 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-18689878
16.
Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses.
iScience
; 12: 102-120, 2019 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30682623
17.
Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins.
Biotechnol Prog
; 35(1): e2724, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30299005
18.
Unravelling mRNA export.
Nat Cell Biol
; 8(7): 645-7, 2006 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16820771
19.
Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness.
Biotechnol Prog
; 34(3): 602-612, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29693321
20.
Strategic deployment of CHO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio.
Biotechnol Prog
; 33(6): 1463-1467, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28480558