Detalhe da pesquisa
1.
Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc Natl Acad Sci U S A
; 115(4): 768-773, 2018 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29311313
2.
The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.
Infect Immun
; 87(1)2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30323030
3.
Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease.
Kidney Int
; 94(6): 1141-1150, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30322716
4.
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
FASEB J
; 31(5): 2210-2219, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28188176
5.
Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent manner.
J Immunol
; 194(7): 3414-21, 2015 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25725105
6.
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.
Proc Natl Acad Sci U S A
; 111(14): 5301-6, 2014 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24706855
7.
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.
Proc Natl Acad Sci U S A
; 110(34): 13916-20, 2013 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-23922389
8.
Reply to Mortensen et al.: The zymogen form of complement component C1.
Proc Natl Acad Sci U S A
; 115(17): E3867-E3868, 2018 04 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29654143
9.
Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.
BMC Biol
; 13: 27, 2015 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-25912189
10.
Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.
FASEB J
; 28(9): 3996-4003, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24868011
11.
Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm.
Proc Natl Acad Sci U S A
; 109(7): E415-22, 2012 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-22308431
12.
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.
PLoS Pathog
; 8(7): e1002793, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22792067
13.
Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection.
J Immunol
; 189(12): 5860-6, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23150716
14.
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
Proc Natl Acad Sci U S A
; 108(18): 7523-8, 2011 May 03.
Artigo
Inglês
| MEDLINE | ID: mdl-21502512
15.
Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency.
J Am Soc Nephrol
; 24(1): 43-52, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23184055
16.
Role of ficolin-A and lectin complement pathway in the innate defense against pathogenic Aspergillus species.
Infect Immun
; 81(5): 1730-40, 2013 May.
Artigo
Inglês
| MEDLINE | ID: mdl-23478320
17.
Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.
Front Immunol
; 14: 1192767, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37325666
18.
Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19.
Front Immunol
; 13: 841759, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35572551
19.
Engineering novel complement activity into a pulmonary surfactant protein.
J Biol Chem
; 285(14): 10546-52, 2010 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20118239
20.
Analogous interactions in initiating complexes of the classical and lectin pathways of complement.
J Immunol
; 182(12): 7708-17, 2009 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19494295