Detalhe da pesquisa
1.
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.
J Biol Chem
; 299(7): 104890, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37286039
2.
Managing hypertriglyceridemia for cardiovascular disease prevention: Lessons from the PROMINENT trial.
Eur J Clin Invest
; : e14227, 2024 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38662591
3.
ELOVL6 deficiency aggravates allergic airway inflammation through the ceramide-S1P pathway in mice.
J Allergy Clin Immunol
; 151(4): 1067-1080.e9, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36592705
4.
Bioactive TNIIIA2 Sequence in Tenascin-C Is Responsible for Macrophage Foam Cell Transformation; Potential of FNIII14 Peptide Derived from Fibronectin in Suppression of Atherosclerotic Plaque Formation.
Int J Mol Sci
; 25(3)2024 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38339104
5.
New balance capability index as a screening tool for mild cognitive impairment.
BMC Geriatr
; 23(1): 74, 2023 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36739383
6.
ELOVL5-mediated fatty acid elongation promotes cellular proliferation and invasion in renal cell carcinoma.
Cancer Sci
; 113(8): 2738-2752, 2022 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-35670054
7.
Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease.
Am J Physiol Gastrointest Liver Physiol
; 323(6): G627-G639, 2022 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36283088
8.
Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling.
FASEB J
; 35(6): e21663, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34042217
9.
CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2.
Biochem Biophys Res Commun
; 562: 146-153, 2021 07 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34052660
10.
High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways.
Biochem Biophys Res Commun
; 582: 35-42, 2021 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34688045
11.
Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice.
Hepatology
; 71(5): 1609-1625, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31529722
12.
Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non-alcoholic steatohepatitis model.
J Gastroenterol Hepatol
; 36(3): 800-810, 2021 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-32870526
13.
Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.
Biochem Biophys Res Commun
; 523(2): 354-360, 2020 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31866012
14.
Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion.
BMC Med Genet
; 21(1): 91, 2020 05 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32375679
15.
Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations.
Int J Mol Sci
; 21(1)2020 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31935812
16.
The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.
Cardiovasc Diabetol
; 18(1): 71, 2019 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31164165
17.
Higher pulse pressure predicts initiation of dialysis in Japanese patients with diabetes.
Diabetes Metab Res Rev
; 35(3): e3120, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30578707
18.
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
Arterioscler Thromb Vasc Biol
; 38(4): 744-756, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29437575
19.
Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome.
Int J Mol Sci
; 20(15)2019 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31357643
20.
Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα.
Biochem Biophys Res Commun
; 499(2): 239-245, 2018 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29567478