Detalhe da pesquisa
1.
The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1b-mediated AML progression.
Blood
; 2024 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38498025
2.
Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.
EMBO J
; 40(1): e106118, 2021 01 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33226141
3.
SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex.
Nucleic Acids Res
; 51(13): 6754-6769, 2023 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37309898
4.
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells.
PLoS Biol
; 19(3): e3001176, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33788831
5.
Transcriptional regulation of multiciliated cell differentiation.
Semin Cell Dev Biol
; 110: 51-60, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32362381
6.
The MRE11 complex: starting from the ends.
Nat Rev Mol Cell Biol
; 12(2): 90-103, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21252998
7.
Functional analysis of TLK2 variants and their proximal interactomes implicates impaired kinase activity and chromatin maintenance defects in their pathogenesis.
J Med Genet
; 59(2): 170-179, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33323470
8.
Defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice.
Development
; 146(8)2019 04 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30936178
9.
Molecular causes of primary microcephaly and related diseases: a report from the UNIA Workshop.
Chromosoma
; 129(2): 115-120, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32424716
10.
PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication.
Mol Cell
; 52(4): 566-73, 2013 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-24267451
11.
GEMC1 is a critical regulator of multiciliated cell differentiation.
EMBO J
; 35(9): 942-60, 2016 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26933123
12.
The Tousled-like kinases regulate genome and epigenome stability: implications in development and disease.
Cell Mol Life Sci
; 76(19): 3827-3841, 2019 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-31302748
13.
NBS1 is required for macrophage homeostasis and functional activity in mice.
Blood
; 126(22): 2502-10, 2015 Nov 26.
Artigo
Inglês
| MEDLINE | ID: mdl-26324700
14.
Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.
Mol Cell
; 34(1): 13-25, 2009 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-19362533
15.
EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.
Nucleic Acids Res
; 43(15): 7371-87, 2015 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-26160886
16.
Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
Genes Dev
; 23(2): 171-80, 2009 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19171781
17.
Positional Enrichment by Proton Analysis (PEPA): A One-Dimensional 1 H-NMR Approach for 13 C Stable Isotope Tracer Studies in Metabolomics.
Angew Chem Int Ed Engl
; 56(13): 3531-3535, 2017 03 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28220994
18.
Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Mol Cell
; 31(1): 21-32, 2008 Jul 11.
Artigo
Inglês
| MEDLINE | ID: mdl-18614044
19.
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome.
PLoS Genet
; 9(8): e1003695, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24009516
20.
E2F4/5-mediated transcriptional control of multiciliated cell differentiation: redundancy or fine-tuning?
Dev Biol
; 446(1): 20-21, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30537487