Detalhe da pesquisa
1.
Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease.
Pharm Res
; 40(6): 1553-1568, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37173537
2.
2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine-derived CDK2 inhibitors as anticancer agents: Design, synthesis & evaluation.
Bioorg Med Chem
; 80: 117158, 2023 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36706608
3.
Discovery of N,4-Di(1H-pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation.
Molecules
; 28(7)2023 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37049714
4.
An overview of CDK3 in cancer: clinical significance and pharmacological implications.
Pharmacol Res
; 180: 106249, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35533805
5.
Proton pump inhibitors may contribute to progression or development of chronic obstructive pulmonary disease-A sequence symmetry analysis approach.
J Clin Pharm Ther
; 46(6): 1687-1694, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34431531
6.
Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance.
Bioorg Chem
; 105: 104394, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33120321
7.
Tripeptide analogues of MG132 as protease inhibitors.
Bioorg Med Chem
; 27(2): 436-441, 2019 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30581047
8.
In Search of Novel CDK8 Inhibitors by Virtual Screening.
J Chem Inf Model
; 57(3): 413-416, 2017 03 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28191946
9.
In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.
Xenobiotica
; 47(6): 461-469, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-27412850
10.
Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome.
Exp Eye Res
; 146: 212-223, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26997634
11.
Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia.
Mol Pharmacol
; 88(2): 380-9, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26044548
12.
Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity.
PLoS Genet
; 8(6): e1002755, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22719265
13.
Chronic Obstructive Pulmonary Disease Adverse Event Signals Associated with Potential Inhibitors of Glutathione Peroxidase 1: A Sequence Symmetry Analysis.
Drug Saf
; 47(1): 59-70, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37995048
14.
Identification of a novel oligomerization disrupting mutation in CRYΑA associated with congenital cataract in a South Australian family.
Hum Mutat
; 34(3): 435-8, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23255486
15.
Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors.
Chemistry
; 19(24): 7975-81, 2013 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-23606616
16.
Combined Structure- and Ligand-Based Approach for the Identification of Inhibitors of AcrAB-TolC in Escherichia coli.
ACS Infect Dis
; 9(12): 2504-2522, 2023 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37888944
17.
Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division.
Front Microbiol
; 13: 967949, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36106080
18.
Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding.
Biomolecules
; 12(7)2022 07 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35883516
19.
A Systematic Review and Meta-Analysis Considering the Risk for Congenital Heart Defects of Antidepressant Classes and Individual Antidepressants.
Drug Saf
; 44(3): 291-312, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33354752
20.
Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate.
Neuropharmacology
; 198: 108755, 2021 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34416268