Detalhe da pesquisa
1.
Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised, placebo-controlled trial.
Lancet
; 402(10412): 1541-1551, 2023 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37738999
2.
Trial of Spesolimab for Generalized Pustular Psoriasis.
N Engl J Med
; 385(26): 2431-2440, 2021 12 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34936739
3.
Generalized pustular psoriasis: A nationwide population-based study using the National Health Data System in France.
J Eur Acad Dermatol Venereol
; 2024 Feb 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38404163
4.
Psychometric validation of the Psoriasis Symptom Scale, Functional Assessment of Chronic Illness Therapy-Fatigue and pain-Visual Analogue Scale in patients with generalized pustular psoriasis.
J Eur Acad Dermatol Venereol
; 2024 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38334243
5.
Rapid and sustained improvements in Generalized Pustular Psoriasis Physician Global Assessment scores with spesolimab for treatment of generalized pustular psoriasis flares in the randomized, placebo-controlled Effisayil 1 study.
J Am Acad Dermatol
; 89(1): 36-44, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36870370
6.
Clinical Characteristics and Outcomes of Generalized Pustular Psoriasis Flares.
Dermatology
; 239(3): 345-354, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36796336
7.
Spesolimab improves patient-reported outcomes in patients with generalized pustular psoriasis: Results from the Effisayil 1 study.
J Eur Acad Dermatol Venereol
; 37(4): 730-736, 2023 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-36527385
8.
Psychometric validation of the generalized pustular psoriasis physician global assessment (GPPGA) and generalized pustular psoriasis area and severity index (GPPASI).
J Eur Acad Dermatol Venereol
; 37(7): 1327-1335, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-36854864
9.
Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis.
J Allergy Clin Immunol
; 149(4): 1402-1412, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34678325
10.
MicroRNAs trigger dissociation of eIF4AI and eIF4AII from target mRNAs in humans.
Mol Cell
; 56(1): 79-89, 2014 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25280105
11.
The degree of hepatic steatosis associates with impaired cardiac and autonomic function.
J Hepatol
; 70(6): 1203-1213, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30769007
12.
The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity.
Br J Dermatol
; 189(1): 138-140, 2023 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37075220
13.
High-intensity interval training: a review of its impact on glucose control and cardiometabolic health.
Diabetologia
; 60(1): 7-23, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27681241
14.
Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis.
N Engl J Med
; 380(10): 981-983, 2019 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30855749
15.
Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial.
Clin Gastroenterol Hepatol
; 15(1): 96-102.e3, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27521509
16.
Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers.
Clin Gastroenterol Hepatol
; 15(10): 1596-1603.e3, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28501537
17.
The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.
Mol Cell
; 36(6): 1007-17, 2009 Dec 25.
Artigo
Inglês
| MEDLINE | ID: mdl-20064466
18.
High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial.
Diabetologia
; 59(1): 56-66, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26350611
19.
Cardiac structure and function are altered in type 2 diabetes and non-alcoholic fatty liver disease and associate with glycemic control.
Cardiovasc Diabetol
; 14: 23, 2015 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25849783
20.
Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial.
Clin Sci (Lond)
; 129(12): 1097-105, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26265792