Detalhe da pesquisa
1.
Partners with a killer: Metabolic signaling promotes inflammatory cell death.
Cell
; 184(17): 4374-4376, 2021 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34416144
2.
Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Immunity
; 53(1): 106-114.e5, 2020 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32553275
3.
Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity
; 51(1): 43-49.e4, 2019 07 16.
Artigo
Inglês
| MEDLINE | ID: mdl-31097341
4.
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.
Nat Immunol
; 16(10): 1025-33, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26343537
5.
Regulation of Synovial γδ T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D.
J Immunol
; 210(1): 61-71, 2023 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36445376
6.
Structural mechanism of DNA recognition by the p204 HIN domain.
Nucleic Acids Res
; 49(5): 2959-2972, 2021 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33619523
7.
NLRX1 has a tail to tell.
Immunity
; 36(3): 311-2, 2012 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-22444625
8.
Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
Proc Natl Acad Sci U S A
; 115(26): 6792-6797, 2018 06 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29891674
9.
The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.
J Biol Chem
; 293(6): 1924-1932, 2018 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29269411
10.
The nucleic acid-sensing inflammasomes.
Immunol Rev
; 265(1): 103-11, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25879287
11.
RAGE Enhances TLR Responses through Binding and Internalization of RNA.
J Immunol
; 197(10): 4118-4126, 2016 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27798148
12.
Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain.
Proc Natl Acad Sci U S A
; 112(17): 5455-60, 2015 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25870276
13.
Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly.
J Immunol
; 192(12): 6028-36, 2014 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24821971
14.
Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc Natl Acad Sci U S A
; 110(17): 6985-90, 2013 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-23569230
15.
Activation and assembly of the inflammasomes through conserved protein domain families.
Apoptosis
; 20(2): 151-6, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25398536
16.
Regulation of gasdermins in pyroptosis and cytokine release.
Adv Immunol
; 158: 75-106, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37453754
17.
SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence.
Viruses
; 15(11)2023 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38005906
18.
PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain.
Genes Dis
; 10(4): 1702-1713, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37397533
19.
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Mol Oncol
; 17(12): 2526-2545, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37149844
20.
Mechanisms of Gasdermin Recognition by Proteases.
J Mol Biol
; 434(4): 167274, 2022 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34599940