Detalhe da pesquisa
1.
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Mol Med
; 27(1): 81, 2021 07 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34294046
2.
Blood and Salivary MicroRNAs for Diagnosis of Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
J Oral Maxillofac Surg
; 79(5): 1082.e1-1082.e13, 2021 May.
Artigo
Inglês
| MEDLINE | ID: mdl-33516682
3.
Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
Bioorg Med Chem Lett
; 28(10): 1964-1971, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29636220
4.
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.
ACS Med Chem Lett
; 15(5): 714-721, 2024 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38746903
5.
Discovery of BIO-8169âA Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.
J Med Chem
; 67(10): 8383-8395, 2024 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38695469
6.
Catalytic asymmetric Petasis reactions of vinylboronates.
J Org Chem
; 78(18): 9415-23, 2013 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-23971730
7.
SIRT6-regulated macrophage efferocytosis epigenetically controls inflammation resolution of diabetic periodontitis.
Theranostics
; 13(1): 231-249, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36593966
8.
Acceleration of Petasis reactions of salicylaldehyde derivatives with molecular sieves.
J Org Chem
; 77(2): 1154-60, 2012 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-22171661
9.
LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance.
Cell Death Differ
; 29(2): 351-365, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34497381
10.
Discovery of 4-aminomethylphenylacetic acids as γ-secretase modulators via a scaffold design approach.
Bioorg Med Chem Lett
; 21(24): 7277-80, 2011 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22061640
11.
Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546.
ACS Med Chem Lett
; 12(7): 1124-1129, 2021 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34267882
12.
Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo.
J Med Chem
; 64(20): 15402-15419, 2021 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34653340
13.
Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors.
ACS Med Chem Lett
; 11(4): 485-490, 2020 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32292554
14.
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors.
J Med Chem
; 62(23): 10740-10756, 2019 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31710475
15.
Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.
Bioorg Med Chem Lett
; 18(15): 4298-302, 2008 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18632269
16.
Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
J Med Chem
; 50(13): 3086-100, 2007 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-17530838
17.
Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension.
Protein Sci
; 26(2): 152-162, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27727493
18.
Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.
J Med Chem
; 49(13): 3770-3, 2006 Jun 29.
Artigo
Inglês
| MEDLINE | ID: mdl-16789734
19.
2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.
J Med Chem
; 49(8): 2568-78, 2006 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-16610800
20.
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity.
J Med Chem
; 49(12): 3563-80, 2006 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16759099