Detalhe da pesquisa
1.
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins.
Biochemistry
; 63(3): 251-263, 2024 Feb 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38243804
2.
Allosteric differences dictate GroEL complementation of E. coli.
FASEB J
; 36(3): e22198, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35199390
3.
Sirtuin 2 Regulates Protein LactoylLys Modifications.
Chembiochem
; 22(12): 2102-2106, 2021 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33725370
4.
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Bioorg Med Chem Lett
; 29(14): 1689-1693, 2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31129054
5.
A one-step, atom economical synthesis of thieno[2,3-d]pyrimidin-4-amine derivatives via a four-component reaction.
European J Org Chem
; 20(2): 3269-3272, 2019 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31857792
6.
Arsenic Compromises Both p97 and Proteasome Functions.
Chem Res Toxicol
; 30(7): 1508-1514, 2017 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28636814
7.
Human polymerase theta helicase positions DNA microhomologies for double-strand break repair.
bioRxiv
; 2024 Apr 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38712090
8.
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78.
J Med Chem
; 66(1): 677-694, 2023 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36516003
9.
Physachenolide C is a Potent, Selective BET Inhibitor.
J Med Chem
; 66(1): 913-933, 2023 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36577036
10.
Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology.
Sci Rep
; 12(1): 8140, 2022 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35581326
11.
Molecular Dynamics Simulations Identify Tractable Lead-like Phenyl-Piperazine Scaffolds as eIF4A1 ATP-competitive Inhibitors.
ACS Omega
; 6(38): 24432-24443, 2021 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34604625
12.
Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL.
mBio
; 12(1)2021 01 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33436430
13.
Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action.
J Med Chem
; 64(21): 15727-15746, 2021 11 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34676755
14.
Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity.
Clin Cancer Res
; 24(17): 4256-4270, 2018 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29844128