Detalhe da pesquisa
1.
Network-based analysis revealed significant interactions between risk genes of severe COVID-19 and host genes interacted with SARS-CoV-2 proteins.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34535795
2.
Design, synthesis and evaluation of new pyrimidine derivatives as EGFRC797S tyrosine kinase inhibitors.
Bioorg Med Chem Lett
; 91: 129381, 2023 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37336419
3.
Progress of small molecules for targeted protein degradation: PROTACs and other technologies.
Drug Dev Res
; 84(2): 337-394, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36606428
4.
Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.
Bioorg Med Chem
; 66: 116803, 2022 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35561631
5.
Overcoming C797S mutation: The challenges and prospects of the fourth-generation EGFR-TKIs.
Bioorg Chem
; 128: 106057, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35964503
6.
The Role of α7nAChR-Mediated Cholinergic Anti-Inflammatory Pathway in Vagal Nerve Regulated Atrial Fibrillation.
Int Heart J
; 62(3): 607-615, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34054001
7.
Co-Culture of Adipose-Derived Stem Cells and Chondrocytes With Transforming Growth Factor-Beta 3 Promotes Chondrogenic Differentiation.
J Craniofac Surg
; 31(8): 2355-2359, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33136890
8.
Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3,4-d]pyrimidine scaffold.
Bioorg Med Chem
; 26(12): 3619-3633, 2018 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29853340
9.
Novel 6-aryl substituted 4-pyrrolidineaminoquinazoline derivatives as potent phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.
Bioorg Med Chem
; 26(8): 2028-2040, 2018 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29534936
10.
Synthesis and evaluation of 2,9-disubstituted 8-phenylthio/phenylsulfinyl-9H-purine as new EGFR inhibitors.
Bioorg Med Chem
; 26(8): 2173-2185, 2018 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29576272
11.
Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.
J Enzyme Inhib Med Chem
; 33(1): 651-656, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29536777
12.
Discovery of 2-(pyridin-2-yl)aniline as a directing group for the sp2 C-H bond amination mediated by cupric acetate.
Org Biomol Chem
; 15(31): 6622-6631, 2017 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28752166
13.
An improved efficient synthesis of the antibacterial agent torezolid.
Chem Pharm Bull (Tokyo)
; 63(2): 143-6, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25491645
14.
Sequential transplantation of exosomes and BMSCs pretreated with hypoxia efficiently facilitates perforator skin flap survival area in rats.
Br J Oral Maxillofac Surg
; 62(4): 361-366, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38521740
15.
Performance of the walking trail making test in older adults with white matter hyperintensities.
World J Psychiatry
; 14(1): 102-110, 2024 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38327891
16.
Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology.
Life Sci
; 336: 122308, 2024 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38030059
17.
Modification of osimertinib to discover new potent EGFRC797S-TK inhibitors.
Eur J Med Chem
; 261: 115865, 2023 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37839342
18.
Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups.
J Med Chem
; 65(19): 13413-13435, 2022 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36173787
19.
Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.
J Med Chem
; 65(6): 4709-4726, 2022 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35254067
20.
Recent Progress of Small Molecule Menin-MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia.
J Med Chem
; 64(21): 15519-15533, 2021 11 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34726905