Clinical and epidemiological aspects of SARS-CoV-2 infection among pregnant and postpartum women in Mozambique: a prospective cohort study.

BACKGROUND: Although there is a significant increase of evidence regarding the prevalence and impact of COVID-19 on maternal and perinatal outcomes, data on the effects of the pandemic on the obstetric population in sub-Saharan African countries are still scarce. Therefore, the study aims were to assess the prevalence and impact of COVID-19 on maternal and neonatal outcomes in the obstetric population at Central Hospital of Maputo (HCM), Mozambique. METHODS: Prospective cohort study conducted at teaching and referral maternity, HCM, from 20 October 2020 to 22 July 2021. We collected maternal and perinatal outcomes up to 6 weeks postpartum of eligible women (pregnant and postpartum women-up to the 14th day postpartum) screened for COVID-19 (individual test for symptomatic participants and pool testing for asymptomatic). The primary outcome was maternal death, Severe Acute Respiratory Syndrome (SARS) and Intensive Care Unit (ICU) admission. We estimated the COVID-19 prevalence and the unadjusted RR (95% CI) for maternal and perinatal outcomes. We used the chi-square or Fisher's exact test to compare categorical variables (two-sided p-value < 0.05 for statistical significance). RESULTS: We included 239 participants. The overall prevalence of COVID-19 was 9.2% (22/239) and in the symptomatic group was 32.4% (11/34). About 50% of the participants with COVID-19 were symptomatic. Moreover, the most frequent symptoms were dyspnoea (33.3%), cough (28.6%), anosmia (23.8%), and fever (19%). Not having a partner, being pregnant, and alcohol consumption were vulnerability factors for SARS-CoV-2 infection. The risk of adverse maternal and neonatal outcomes (abortion, foetal death, preterm birth, Apgar, and NICU admission) was not significantly increased with COVID-19. Moreover, we did not observe a significant difference in the primary outcomes (SARS, ICU admission and maternal death) between COVID-19 positive and COVID-19 negative groups. CONCLUSION: The prevalence of COVID-19 in the obstetric population is higher than in the general population, and fifty percent of pregnant and postpartum women with COVID-19 infection are asymptomatic. Not having a partner and alcohol consumption were factors of greatest vulnerability to SARS-COV-2 infection. Moreover, being pregnant versus postpartum was associated with increased vulnerability to COVID-19. Data suggest that pregnant women with COVID-19 may have a higher frequency of  COVID-19 infection, reinforcing the need for universal testing, adequate follow-up for this population, and increasing COVID-19 therapy facilities in Mozambique. Moreover, provide counselling during Antenatal care for COVID-19 preventive measures. However, more prospective and robust studies are needed to assess these findings.

Endometriosis and assisted reproductive techniques independently related to mother-child morbidities: a French longitudinal national study.

RESEARCH QUESTION: Does endometriosis increase obstetric and neonatal complications, and does assisted reproductive technology (ART) cause additional risk of maternal or fetal morbidity? DESIGN: A nationwide cohort study (2013-2018) comparing maternal and perinatal morbidities in three groups of single pregnancies: spontaneous pregnancies without endometriosis; spontaneous pregnancies with endometriosis; and ART pregnancies in women with endometriosis. RESULTS: Mean maternal ages were 30.0 (SD = 5.3), 31.7 (SD = 4.8) and 33.1 years (SD = 4.0), for spontaneous conceptions, spontaneous conceptions with endometriosis and ART pregnancies with endometriosis groups, respectively (P < 0.0001). Comparison of spontaneous conceptions with endometriosis and spontaneous conceptions: endometriosis independently increased the risk of venous thrombosis (adjusted OR [aOR] 1.51, P < 0.001), pre-eclampsia (aOR 1.29, P < 0.001), placenta previa (aOR 2.62, P < 0.001), placental abruption (aOR 1.54, P < 0.001), premature birth (aOR 1.37, P < 0.001), small for gestational age (aOR 1.05, P < 0.001) and malformations (aOR 1.06, P = 0.049). Comparison of ART pregnancies with endometriosis and spontaneous conceptions with endometriosis: ART increased the risk of placenta previa (aOR 2.43, 95% CI 2.10 to 2.82, P < 0.001), premature birth (aOR 1.42, 95% CI 1.29 to 1.55, P < 0.001) and small for gestational age (aOR 1.18, 95% CI 1.10 to 1.27, P < 0.001), independently from the effect of endometriosis. Risk of pre-eclampsia, placental abruption or congenital malformations was not increased with ART. CONCLUSION: Endometriosis is an independent risk factor for mother and child morbidities. Maternal morbidity and perinatal morbidity were significantly increased by ART in addition to endometriosis; however, some perinatal and maternal morbidity risks were increasingly linked to pathologies related to infertility.

Hypertensive disorders in pregnancy - Trends over eight years: A population-based cohort study.

OBJECTIVE: To describe the incidence and trends of hypertensive disorders of pregnancy and adverse pregnancy outcomes in recent years in Victoria, Australia. DESIGN: Retrospective population-based cohort study, 2010 to 2017. SETTING: State of Victoria, Australia. PARTICIPANTS: Population-based cohort study. MAIN OUTCOME MEASURES: Incidence of hypertensive disorders and its subtypes over time. Composite of major adverse maternal and perinatal outcome. RESULTS: The incidence of hypertensive disorders (n = 36,406/614,524 pregnancies with 624,193 births) and all its subtypes has been stable, (n = 4,192/73,235 = 5.7% in 2010 to 4,601/78,576 = 5.9% in 2017). Compared to no hypertension, hypertensive disorders were associated with medically-initiated birth (aOR 4.70 [4.56, 4.84]), caesarean section (aOR 1.46 [1.43, 1.50]), placental abruption (aOR 1.94 [1.69, 2.22]), maternal intensive care or high-dependency unit admission (aOR 6.80 [6.45, 7.17]), composite of major adverse maternal outcome (aOR 3.87 [3.70, 4.04]), and composite of major adverse perinatal outcome (aOR 1.63 [1.56, 1.70]). The worst maternal and perinatal outcomes were among women with superimposed and early preterm preeclampsia. CONCLUSION: The incidence of all hypertensive disorders in pregnancy has remained stable over time. Early-onset preeclampsia and superimposed preeclampsia were most strongly associated with adverse pregnancy outcomes.

Multiple Gestations and Assisted Reproductive Technologies: Qualitative Study of the Discourse of Health Professionals in Spain.

Multiple gestations have become an increasing phenomenon that has impacted public health globally, largely due to the application of assisted reproductive technologies. The objective of this work was to find out the discourse that the health professionals involved in its follow-up have in our context. For this, a qualitative methodology was chosen, with semi-structured interviews recorded in audio, prior authorisation, and transcribed verbatim. It was based on a script designed for this purpose, with the following analysis categories: the current trend of multiple gestations, impact, and follow-up. The content analysis was based on the experiences, knowledge, and perceptions of the professionals interviewed. Professionals stated that the current socioeconomic and legal context hinders a single embryo transfer policy that decreases multiple gestation rates. They emphasised the importance of the psychic impact of such gestations on the couple, on the mother in particular, as well as the economic effect on families, health, and society in general. They expressed the need to create specific protocols to assist these gestations. Midwives, in particular, demanded that the health administration recognise and support the differentiated care they perform with this type of gestation. Work on specific models is needed to adequately size the impact of multiple gestations, as well as to generate social health policies that lead to co-responsible reconciliation measures that favour women having one pregnancy at a time.

Treatment of severe hypertension during pregnancy: we still do not know what the best option is.

Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unclear. Moreover, given the lack of well-designed randomized controlled trials with standardized key outcomes, the current choice of antihypertensive medications depends rather on clinicians' preference. Furthermore, data on long-term outcomes of offspring is not available. Therefore, there is an urgent need for randomized trials comparing different anti-hypertensive options to address efficacy and safety questions.

Obstetric and perinatal outcomes in women ≥40years of age: Associations with fetal growth disorders.

BACKGROUND: Evidence indicates that advanced maternal age is associated with adverse obstetric and perinatal outcomes. The purpose of this study was to evaluate pregnancy outcomes in women of advanced maternal age (≥40years). METHODS: Using a prospective study design, data were collected by the Department of Obstetrics at the San Joan de Deu Hospital of Barcelona during the 1 June 2009 to 31 May 2012 period. The results were compared across three maternal age groups (≥40 [n=654], 35-39 [n=2781], and <35 [n=7893] years). RESULTS: Of the 11328 births recorded during the study period, pregnancy-related complications were more common in women ≥40years of age. The most common disorder was diabetes (8.5% in the ≥40, 5.3% in the 35-39, and 3.0% in the <35years age groups). The women ≥40years of age also had significantly more premature births (p=0.001) and cesarean sections (17% in the ≥40, 12.5% in the 35-39, and 7.9% in the <35-year age groups; p=0.001). Intrauterine growth retardation was significantly more frequent in women aged ≥40years (17.4% in the ≥40, 15% in the 35-39, and 14.0% in the <35-year age groups; p=0.03). Fetal macrosomia was significantly more common in women ≥40years (15.4% in the ≥40, 12.6% in the 35-39, and 12% in the <35-year age groups; p=0.03). CONCLUSION: Maternal age ≥40years was associated with poorer obstetric and perinatal outcomes and increased the risks of cesarean section, intrauterine growth retardation, and fetal macrosomia.

Trastornos hipertensivos durante el embarazo en gestantes del Policlínico Universitario Santa Clara (2015-2016) / Hypertensive disorders during pregnancy in the University Polyclinic Santa Clara (2015-2016)

Introducción: la preeclampsia es la complicación médica más frecuente del embarazo. En Cuba se ha encontrado una incidencia entre 5 y 10 por ciento, y constituye una de las primeras causas de morbilidad materna y perinatal. Objetivos: describir el comportamiento de los trastornos hipertensivos en las gestantes. Métodos: se realizó una investigación de tipo descriptiva transversal en el Policlínico Santa Clara en el periodo 2015-2016. La población de estudio estuvo constituida por la totalidad (210) las gestantes que pertenecen al policlínico Santa Clara, para la selección de la muestra se empleó un muestreo no probabilístico por criterios, quedando finalmente constituida por 52 pacientes. Resultados: los trastornos hipertensivos del embarazo es una entidad frecuente en el área de salud con repercusión sobre las tasas de morbilidad materna en 20 pacientes (38,5 por ciento), la morbilidad perinatal en 17 pacientes (32,7 por ciento) y la mortalidad en 2 pacientes (3,8 por ciento). Conclusiones: estos trastornos se presentan más en mujeres en las edades extremas de la vida reproductiva y con trastornos nutricionales. Las hipercolesterolemia y la HTA crónica están entre las principales afecciones asociadas. Se presentó mayormente en nulíparas y primíparas con embarazos a término completos y hubo elevado índice de inducciones del parto y cesáreas. La morbilidad puerperal fue elevada con prevalencia de la anemia y también tuvo repercusión sobre el peso y estado de los recién nacidos(AU)

Introduction: Preeclampsia is the most frequent medical complication of pregnancy. In Cuba, an incidence of between 5 and 10 percent has been found and is one of the earliest causes of maternal and perinatal morbidity. Objectives: to describe the behavior of hypertensive disorders in pregnant women. Methods: a cross-sectional descriptive study was carried out in the Santa Clara Polyclinic in the period 2015-2016. The study population consisted of all the (210) pregnant women who belonged to the Santa Clara polyclinic. For the selection of the sample a non-probabilistic sampling was used by criteria, and finally it was constituted by 52 patients. Results: hypertensive disorders of pregnancy are a frequent entity in the health area with repercussions on maternal morbidity rates in 20 patients (38.5 percent), perinatal morbidity in 17 patients (32.7 percent) and mortality in 2 patients (3.8 percent). Conclusions: these disorders present more in women in the extreme ages of reproductive life and with nutritional disorders. Hypercholesterolemia and chronic hypertension are among the main associated conditions. It was present mainly in nulliparous and primiparous women with full term pregnancies and there was a high index of labor induction and cesarean section. Puerperal morbidity was high with prevalence of anemia and also had an impact on the weight and condition of newborns(AU)

Trastornos hipertensivos durante el embarazo en gestantes del Policlínico Universitario Santa Clara (2015-2016) / Hypertensive disorders during pregnancy in the University Polyclinic Santa Clara (2015-2016)

Introducción: la preeclampsia es la complicación médica más frecuente del embarazo. En Cuba se ha encontrado una incidencia entre 5 y 10 por ciento, y constituye una de las primeras causas de morbilidad materna y perinatal. Objetivos: describir el comportamiento de los trastornos hipertensivos en las gestantes. Métodos: se realizó una investigación de tipo descriptiva transversal en el Policlínico Santa Clara en el periodo 2015-2016. La población de estudio estuvo constituida por la totalidad (210) las gestantes que pertenecen al policlínico Santa Clara, para la selección de la muestra se empleó un muestreo no probabilístico por criterios, quedando finalmente constituida por 52 pacientes. Resultados: los trastornos hipertensivos del embarazo es una entidad frecuente en el área de salud con repercusión sobre las tasas de morbilidad materna en 20 pacientes (38,5 por ciento), la morbilidad perinatal en 17 pacientes (32,7 por ciento) y la mortalidad en 2 pacientes (3,8 por ciento). Conclusiones: estos trastornos se presentan más en mujeres en las edades extremas de la vida reproductiva y con trastornos nutricionales. Las hipercolesterolemia y la HTA crónica están entre las principales afecciones asociadas. Se presentó mayormente en nulíparas y primíparas con embarazos a término completos y hubo elevado índice de inducciones del parto y cesáreas. La morbilidad puerperal fue elevada con prevalencia de la anemia y también tuvo repercusión sobre el peso y estado de los recién nacidos(AU)

Introduction: Preeclampsia is the most frequent medical complication of pregnancy. In Cuba, an incidence of between 5 and 10 percent has been found and is one of the earliest causes of maternal and perinatal morbidity. Objectives: to describe the behavior of hypertensive disorders in pregnant women. Methods: a cross-sectional descriptive study was carried out in the Santa Clara Polyclinic in the period 2015-2016. The study population consisted of all the (210) pregnant women who belonged to the Santa Clara polyclinic. For the selection of the sample a non-probabilistic sampling was used by criteria, and finally it was constituted by 52 patients. Results: hypertensive disorders of pregnancy are a frequent entity in the health area with repercussions on maternal morbidity rates in 20 patients (38.5 percent), perinatal morbidity in 17 patients (32.7 percent) and mortality in 2 patients (3.8 percent). Conclusions: these disorders present more in women in the extreme ages of reproductive life and with nutritional disorders. Hypercholesterolemia and chronic hypertension are among the main associated conditions. It was present mainly in nulliparous and primiparous women with full term pregnancies and there was a high index of labor induction and cesarean section. Puerperal morbidity was high with prevalence of anemia and also had an impact on the weight and condition of newborns(AU)

Diagnóstico, Evaluación y Manejo de la Enfermedad Renal en el Embarazo / Diagnosis, Evaluation, and Management of renal diseases during Pregnancy

Introducción: La elevada prevalencia de enfermedad renal crónica y otras enfermedades no transmisibles crónicas, unido al incremento en la edad de embarazo ha generado nuevas investigaciones y evidencias de la relación entre la enfermedad renal crónica, el embarazo y los resultados para la madre y el feto. Objetivo: Exponer las mejores prácticas actuales y ofrece una aproximación al diagnóstico, evaluación y tratamiento de la enfermedad renal en el contexto del embarazo y su repercusión en términos de morbilidad y mortalidad para la madre y el feto. Material y Métodos: Se realizó un análisis de la literatura describiendo los mejores resultados clínicos basado en los avances científicos a la fecha actual. Resultados: Se enfatiza la evolución continua entre el daño renal agudo (incipiente) y la falla renal aguda (con necesidad de métodos dialíticos sustitutivos), también de importancia pronóstica con incrementos en la mortalidad materna asociados a pequeños incrementos en la creatinina sérica. Conclusiones: Tanto el desarrollo de un daño renal agudo, la falla renal aguda y la enfermedad renal crónica son causas importantes de morbilidad y mortalidad materno fetal(AU)

Introduction: The high prevalence of chronic kidney disease and others non contagiables diseases, jointly with its increasing frequency in gestational age women have generated new investigations and evidences of the relationship between the chronic renal diseases, the pregnancy and its consequence for the mother and fetus.Objective: This paper summarizes the best practice up to this date and provides a reasonable approach to the diagnosis, evaluation, and treatment of the Renal Disease Disorders of Pregnancy to evaluate the impact of them on maternal and fetal morbidity and mortality.Material and Methods: An analysis of the published literature of the subject was performed, describing the best clinical results based on scientific advances available today. Results: Was emphasized the continuum evolution between acute kidney damage (incipient injury) and acute kidney failure (need to dialysis) also of importance for prognosis, with increasing of the mortality associated with small increases in serum creatinine. Conclusions: The acute kidney diseases/ acute renal failure and chronic renal diseases are important causes of maternal and perinatal morbidity - mortality(AU)

Diagnóstico, Evaluación y Manejo de la Enfermedad Renal en el Embarazo / Diagnosis, Evaluation, and Management of renal diseases during Pregnancy

Introducción: La elevada prevalencia de enfermedad renal crónica y otras enfermedades no transmisibles crónicas, unido al incremento en la edad de embarazo ha generado nuevas investigaciones y evidencias de la relación entre la enfermedad renal crónica, el embarazo y los resultados para la madre y el feto. Objetivo: Exponer las mejores prácticas actuales y ofrece una aproximación al diagnóstico, evaluación y tratamiento de la enfermedad renal en el contexto del embarazo y su repercusión en términos de morbilidad y mortalidad para la madre y el feto. Material y Métodos: Se realizó un análisis de la literatura describiendo los mejores resultados clínicos basado en los avances científicos a la fecha actual. Resultados: Se enfatiza la evolución continua entre el daño renal agudo (incipiente) y la falla renal aguda (con necesidad de métodos dialíticos sustitutivos), también de importancia pronóstica con incrementos en la mortalidad materna asociados a pequeños incrementos en la creatinina sérica. Conclusiones: Tanto el desarrollo de un daño renal agudo, la falla renal aguda y la enfermedad renal crónica son causas importantes de morbilidad y mortalidad materno fetal(AU)

Introduction: The high prevalence of chronic kidney disease and others non contagiables diseases, jointly with its increasing frequency in gestational age women have generated new investigations and evidences of the relationship between the chronic renal diseases, the pregnancy and its consequence for the mother and fetus. Objective: This paper summarizes the best practice up to this date and provides a reasonable approach to the diagnosis, evaluation, and treatment of the Renal Disease Disorders of Pregnancy to evaluate the impact of them on maternal and fetal morbidity and mortality. Material and Methods: An analysis of the published literature of the subject was performed, describing the best clinical results based on scientific advances available today. Results: Was emphasized the continuum evolution between acute kidney damage (incipient injury) and acute kidney failure (need to dialysis) also of importance for prognosis, with increasing of the mortality associated with small increases in serum creatinine. Conclusions: The acute kidney diseases/ acute renal failure and chronic renal diseases are important causes of maternal and perinatal morbidity - mortality(AU)

Morbilidad y mortalidad materna y perinatal en pacientes con macrosomía fetal / Maternal and perinatal morbidity and mortality in patients with foetal macrosomia

Introducción: la macrosomía fetal se ha encontrado asociada a una mayor morbilidad y mortalidad, tanto infantil como materna.Objetivo: identificar la morbilidad y mortalidad materna y perinatal presente en pacientes con macrosomía fetal.Métodos: se realizó un estudio transversal descriptivo para identificar la morbilidad y la mortalidad materna y perinatal presente en pacientes con macrosomía fetal en el Hospital Universitario Ginecobstétrico Mariana Grajales de Santa Clara, Villa Clara, enero de 2009 a diciembre del 2010, el universo de trabajo quedó conformado por todas las pacientes que tuvieron un parto de macrosómico 557, el cual coincidió con la muestra, las variables incluidas fueron: morbilidad y mortalidad materna y perinatal, momento del diagnóstico, tipo de parto, grado de la macrosomía y trauma al nacer. Se utilizó la estadística descriptiva e inferencial resumiéndose la información en forma de tablas.Resultados: la hemorragia obstétrica fue la principal morbilidad materna 80 casos (58,0 por ciento), el trauma al nacer fue la morbilidad perinatal más frecuente con 33 casos (41,8 por ciento) y no existió asociación estadística significativa entre el trauma al nacer y el grado de macrosomía con X2= 43.4 y p=0.120.Conclusiones: en el periodo de estudio se observó en las pacientes con macrosomía fetal: morbilidad materna, relacionada con hemorragia posparto y morbilidad perinatal, relacionada con trauma al nacer, el grado de la macrosomía y el trauma al nacer fueron variables independientes(AU)

Introduction: foetal macrosomia has been associated with higher morbidity and mortality rates, in both the infant and the mother.Objective: to identify maternal and perinatal morbidity and mortality in patients with foetal macrosomia.Methods: across-sectional descriptive study was performed to identify maternal and foetal morbidity and mortality in patients with foetal macrosomia, at Mariana Grajales Gynaecobstetric University Hospital of Santa Clara City, Villa Clara Province, from January 2009 to December 2010. The sample group was made up of all the patients who had macrosomic labor (557), which coincided with the sample. The variables included were maternal and perinatal morbidity and mortality, moment of the diagnosis, type of labor, degree of macrosomia and birth trauma. Descriptive and inferential statistics were used; and the information was summarized in charts.Results: obstetrical haemorrhage was the main cause of maternal morbidity (80 cases, 58.0 percent), birth trauma was the most frequent perinatal morbidity (33 cases, 42.8 percent) and there was not any significant statistical relationship between birth trauma and the degree of macrosomia (X2= 43.4 y p=0.120).Conclusions: in the period of study, the patients with foetal macrosomia presented, as it was observed: maternal morbidity, associated to postpartum haemorrhage; and perinatal morbidity, associated to birth trauma. The degree of macrosomia and birth trauma were independent variables(AU)

Perfil epidemiológico y perinatal de pacientes con preeclampsia / Epidemiological and perinatal profile of preeclampsia patients

Introducción: la preeclampsia es un problema obstétrico mayor que acarrea importante morbilidad y mortalidad materna y perinatal por los trastornos sistémicos asociados. Objetivo: comparar los resultados maternos y perinatales en gestantes que cursaron con preeclampsia en sus diferentes presentaciones clínicas. Métodos: estudio prospectivo, descriptivo, transversal, realizado en el hospital "Enrique Cabrera", desde el 1ro. de enero de 2010 al 31 diciembre de 2011. De las gestantes con trastornos hipertensivos (n = 293), se eligieron aquellas con preeclampsia (n = 89) y se dividieron en tres grupos: preeclampsia leve (n = 30), preeclampsia grave (n = 48) y preeclampsia sobreañadida (n = 11). Variables epidemiológicas, obstétricas y perinatales se procesaron por el sistema estadístico SPSS-11,5, utilizando estadística descriptiva, comparación de proporciones mediante la prueba de Chicuadrado y estimado de medias de variables cuantitativas con ANOVA-Eta, considerando la diferencia estadísticamente significativa p £ 0,05. Resultados: predominaron las adolescentes en la preeclampsia grave (25 %) y las ³ 35 años en la preeclampsia sobreañadida (p = 0,002), la obesidad también prevaleció en la preeclampsia sobreañadida (54,5 %, p = 0,01). La mayoría del grupo con preeclampsia leve (60 %) y preeclampsia grave (64,6 %) eran nulíparas, p = 0,009. Fue significativo el índice de prematuridad de la preeclampsia grave (43,8 %, p = 0,005) y el parto por cesárea señoreó en todos los grupos, fundamentalmente en la preeclampsia grave (93,8 %, p = 0,000). La media del peso al nacer fue significativamente inferior en la preeclampsia grave (2 451 g, p = 0,01). Conclusiones: no hubo grandes diferencias en cuanto a los resultados perinatales entre las pacientes que cursaron con los distintos grados de severidad de la preeclampsia.

Introduction: preeclampsia is a major obstetric problem that carries significant morbidity and maternal and perinatal mortality due to associated systemic disorders. Objective: to compare maternal and perinatal outcomes in pregnant women who had preeclampsia in their different clinical presentations. Methods: a prospective, descriptive, cross-sectional study was conducted at Enrique Cabrera hospital from January 1st, 2010 to December 31st 2011. Out of the pregnant women with hypertensive disorders (n = 293), those with preeclampsia (n = 89) were chosen; and they were divided into three groups, mild preeclampsia (n = 30), severe preeclampsia (n = 48) and superimposed preeclampsia (n = 11). Epidemiological, obstetric, and perinatal variables were processed by the SPSS-11, 5 statistical systems, using descriptive statistics, comparison of proportions by Chi-square test and the estimated mean of quantitative variables with ANOVA-Eta, considering the statistically significant difference p ? 0.05. Results: the adolescents had more severe preeclampsia (25 %) and ³ 35 year old patients in the superimposed preeclampsia (p = 0.002), obesity also prevailed in the superimposed preeclampsia (54.5 %, p = 0.01). Most of the patients in the mild PE group (60 %) and severe preeclampsia (64.6 %) were nulliparous, p = 0.009. Prematurity index of severe preeclampsia (43.8 %, p = 0.005) was significant; cesarean delivery was high in all groups, mainly in severe preeclampsia (93.8 %, p = 0.000). The mean birth weight was significantly lower in severe preeclampsia (2 451 g, p = 0.01). Conclusions: there were no major differences in perinatal outcomes among patients who were enrolled with various degrees of preeclampsia severity.