1.
Fitoterapia
; 137: 104264, 2019 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31299275
RESUMO
Five undescribed triterpene-type saponins, parkibicolorosides A-E, a cassane-type diterpene, and a known trimethoxy benzene glucoside were isolated from the roots of Parkia bicolor A. Chev. Their structures were elucidated by different spectroscopic methods including 1D- and 2D-NMR experiments as well as HR-ESI-MS analysis. Their cytotoxic activity against the chronic myeloid leukemia (K562) cell line was evaluated. The monosaccharides saponins exhibited a moderate antiproliferative activity with IC50 ranging from 48.49⯱â¯0.16 to 81.66⯱â¯0.17⯵M.