1.
Mol Cell Oncol
; 8(6): 1996318, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35419480
RESUMO
The early splicing complex A occupies at least eighty nucleotides of intron, in which U2AF covers the polypyrimidine tract. SPF45 (RBM17) functionally substitutes for U2AF on a subset of short introns. Since SPF45 expression confers resistance to various anticancer drugs, SPF45-dependent splicing may play a critical role in multidrug resistance.