Dairy Products and Cancer Risk in a Northern Sweden Population.

The role of dairy products in cancer is unclear. We assessed consumption of fermented milk, non-fermented milk, cheese, and butter, estimated from semi-quantitative food frequency questionnaires, in relation to prospective risk of breast, prostate, colorectal, smoking-, and obesity-related cancers in 101,235 subjects, including 12,552 cancer cases, in the population-based Northern Sweden Health and Disease Study. Most analyses (n = 20) rendered null results. In men, we observed an increased prostate cancer risk among high-consumers of cheese (hazard ratio (HR) for highest vs. lowest quintile (Q5-Q1), 1.11; 95% CI, 0.97-1.27; Ptrend = 0.013). In women, high-consumers of cheese had a decreased risk of overall cancer (HR Q5-Q1, 0.95; 95% CI, 0.88-1.04; Ptrend = 0.039), smoking-related (HR Q5-Q1, 0.84; 95% CI, 0.72-0.97; Ptrend ≤ 0.001), and colorectal cancers (HR Q5-Q1, 0.82; 95% CI, 0.63-1.07; Ptrend = 0.048). Butter yielded a weak decreased obesity-related cancer risk in women (HR Q5-Q1, 0.91; 95% CI, 0.81-1.02; Ptrend = 0.049). Fermented milk yielded HRs below zero in women, but with no clear linear associations. In conclusion, this study does not support any major adverse or beneficial effects of fermented milk, non-fermented milk, cheese, and butter in the diet from a cancer risk perspective.

Theoretical Effects of Substituting Butter with Margarine on Risk of Cardiovascular Disease.

BACKGROUND: Several recent articles have called into question the deleterious effects of high animal fat diets due to mixed results from epidemiologic studies and the lack of clinical trial evidence in meta-analyses of dietary intervention trials. We were interested in examining the theoretical effects of substituting plant-based fats from different types of margarine for animal-based fat from butter on the risk of atherosclerosis-related cardiovascular disease (CVD). METHODS: We prospectively studied 71,410 women, aged 50-79 years, and evaluated their risk for clinical myocardial infarction (MI), total coronary heart disease (CHD), ischemic stroke, and atherosclerosis-related CVD with an average of 13.2 years of follow-up. Butter and margarine intakes were obtained at baseline and year 3 by means of a validated food frequency questionnaire. Cox proportional hazards regression using a cumulative average diet method was used to estimate the theoretical effect of substituting 1 teaspoon/day of three types of margarine for the same amount of butter. RESULTS: Substituting butter or stick margarine with tub margarine was associated with lower risk of MI (HRs = 0.95 and 0.91). Subgroup analyses, which evaluated these substitutions among participants with a single source of spreadable fat, showed stronger associations for MI (HRs = 0.92 and 0.87). Outcomes of total CHD, ischemic stroke, and atherosclerosis-related CVD showed wide confidence intervals but the same trends as the MI results. CONCLUSIONS: This theoretical dietary substitution analysis suggests that substituting butter and stick margarine with tub margarine when spreadable fats are eaten may be associated with reduced risk of myocardial infarction.

Margarine consumption, asthma, and allergy in young adults: results of the German National Health Survey 1998.

PURPOSE: To examine whether frequent intake of margarine is associated with allergy prevalence in adults using data of a representative national health survey. METHODS: Data on 7124 subjects aged 18 to 79 years were obtained from the German National Health Survey 1998. Confounder-adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated by multiple logistic regression, using the frequency of intake of low-fat butter, regular and low-fat margarine as explanatory variable in relation to frequent intake of regular butter as reference group. RESULTS: Frequent intake of margarine of any kind was positively associated with current asthma during the past 12 months in young adults aged 18 to 29 years (aOR, 2.33; 95% CI, 1.03-5.26). In subgroup analysis, the positive association was confined to frequent intake of low-fat margarine (4.51; 1.78-11.43) or the combination of low-fat margarine and low-fat butter (4.79; 1.84-12.44). Consumption of margarine of any kind was not related to hay fever, atopic dermatitis, and atopic sensitization to inhalant allergens. CONCLUSIONS: Frequent intake of margarine rich in n-6 PUFA is not consistently associated with allergic diseases in adults. Other constituents of low-fat margarine or certain dietary habits and lifestyle factors, characterized by use of low-fat margarine, may be related to current asthma.

Aplicação da análise de componentes principais para a determinação do estágio de deterioração em manteigas de garrafa / The use of principal components analysis for determination of the deterioration stage in ‘manteigas de garrafa’

A manteiga de garrafa, também conhecida como manteiga da terra, é um produto abundante em gordura anidra, sendo assim está susceptível as reações de deterioração conhecidas como rancidez, tanto hidrolítica quanto oxidativa, responsáveis por alterações sensoriais indesejáveis, o que diminuem a qualidade nutricional e geram impacto econômico para os produtores. Diante disso, o objetivo deste trabalho foi identificar os produtos de acordo com o seu estágio de deterioração, quanto aos aspectos físico-químicos: pH, umidade, turbidez, condutividade, concentração de sólidos, ponto de fusão, índice de acidez e peróxido, utilizando a análise de componentes principais (ACP), para a interpretação dos dados. O modelo estatístico se mostrou eficiente na separação em grupos das amostras de manteiga com armazenamento de 30, 60 e 90 dias.

Análise discriminante como ferramenta de identificação do tempo de produção e armazenamento da manteiga de garrafa / Discriminant analysis as tool to identification of the time then production and storage of ‘manteiga de garrafa’

A manteiga de garrafa é um produto de cunho regional e cultural do norte mineiro e nordeste do país, onde é ofertada em feiras de comércio livre, sem embalagem adequada e rotulagem, dado que é um produto lipídico, a sua exposição a luz, sujeita o produto a reação de oxidação, que reduz o tempo de vida útil. Em decorrência deste fato o presente trabalho utilizou a análise discriminante, como ferramenta para enquadrar dados físico-químicos de manteigas de garrafa, acerca dos tempos de 30, 60 e 90 dias corridos de armazenagem, objetivando predizer o prazo em que o produto foi obtido. O método estatístico apontou como variáveis de maior impacto, ao decorrer do tempo, sendo a turbidez e o ponto de fusão da amostra e mostrou-se eficaz na separação dos períodos de estocagem avaliados, permitindo predizer o tempo de armazenamento das amostras.

Predictors of usage and fatty acid composition of cooking fats in Bogotá, Colombia.

OBJECTIVE: To examine correlates of home usage of commercially available cooking fats in Bogotá, Colombia and to determine their fatty acid composition. DESIGN: Cross-sectional survey. SETTING: Bogotá, Colombia. SUBJECTS: A representative sample of low- and middle-income families (n 2408). RESULTS: The types of fat primarily used for cooking at home were mixed vegetable oils (66 %), sunflower oil (21 %) and other oils/fats including margarine (13 %). In multivariate analysis, usage of sunflower oil as the primary cooking fat was positively related to home ownership, age of the father and health as a reason for choosing the main cooking fat, and inversely associated with the number of people per room and an index of household food insecurity. The trans fat content of sunflower oil was unexpectedly higher (mean 4.2 %, range 2.2-8.6) than that of the vegetable mixture oils (mean 3.1 %, range 1.1-6.5). CONCLUSIONS: Vegetable oils are the primary home cooking fats in Bogotá, Colombia. Higher socio-economic status is associated with usage of sunflower oil. Paradoxically, oblivious to the higher trans content of sunflower oil and the negligible amount of n-3 fatty acids, families commonly reported 'health' as a reason to choose sunflower over other oils.

Use of butter and cheese in 10 European countries: a case of contrasting educational differences.

BACKGROUND: This paper aims to analyse socioeconomic variation in the use of cheese and butter in Europe by reviewing existing dietary surveys. It explores whether socioeconomic differences in the intake of these foods follow a similar pattern in all countries. METHODS: An overview of available studies on socioeconomic differences in food habits in Europe over the period 1985-1997 was performed. Twenty studies from 10 countries included information on cheese and butter. A simple directional vote-counting method was used to register the association between educational level and consumption of cheese and butter (animal fat) for each study. FAO's food balance sheets were used to classify the countries according to consumption trends of these foodstuffs. RESULTS: In all countries higher social classes used more cheese than lower classes. The results for butter were less consistent. In the Nordic countries higher social classes used less butter than lower ones. In the other countries an opposite pattern or no differences could be observed. However, in countries where the use of both butter and animal fats could be analysed, animal fats were used more by the lower social classes. CONCLUSIONS: Higher and lower socioeconomic groups have different sources of saturated fats. Higher social classes use more cheese whereas lower social classes use more butter or animal fats. This can be observed especially in countries where the consumption of cheese is increasing and that of butter decreasing. Higher social classes prefer modern foods, lower classes traditional foods.