Detalhe da pesquisa
1.
Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation.
Bioorg Med Chem Lett
; 102: 129673, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38408511
2.
Synthesis of New D-π-A Phenothiazine-Based Fluorescent Dyes: Aggregation Induced Emission and Antibacterial Activity.
J Fluoresc
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38647963
3.
Development of certain benzylidene coumarin derivatives as anti-prostate cancer agents targeting EGFR and PI3Kß kinases.
J Enzyme Inhib Med Chem
; 39(1): 2311157, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348846
4.
Quinazoline-chalcone hybrids as HDAC/EGFR dual inhibitors: Design, synthesis, mechanistic, and in-silico studies of potential anticancer activity against multiple myeloma.
Arch Pharm (Weinheim)
; 357(5): e2300626, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297894
5.
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies.
Molecules
; 29(2)2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38257358
6.
Diagnostic accuracy of point-of-care knee ultrasound for evaluation of meniscus and collateral ligaments pathology in comparison with MRI.
Acta Radiol
; 64(7): 2283-2292, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34851172
7.
Harnessing pyrimidine as a building block for histone deacetylase inhibitors.
Arch Pharm (Weinheim)
; 356(10): e2300208, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462396
8.
New 1,3,4-oxadiazole-chalcone/benzimidazole hybrids as potent antiproliferative agents.
Arch Pharm (Weinheim)
; 356(2): e2200357, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351754
9.
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties.
Arch Pharm (Weinheim)
; 356(4): e2200464, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36526595
10.
Design, Synthesis, Antiproliferative Actions, and DFT Studies of New Bis-Pyrazoline Derivatives as Dual EGFR/BRAFV600E Inhibitors.
Int J Mol Sci
; 24(10)2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240450
11.
Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation.
Molecules
; 28(18)2023 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764297
12.
Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAFV600E Inhibitory Pathways.
Molecules
; 28(18)2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764362
13.
New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus.
Bioorg Med Chem
; 73: 117004, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36148773
14.
Functionalization of cotton fabrics with titanium oxide doped silver nanoparticles: Antimicrobial and UV protection activities.
Luminescence
; 37(5): 854-864, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304819
15.
Effect of different surface treatments on the bond strength of milled polyetheretherketone posts.
J Prosthet Dent
; 127(6): 866-874, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495042
16.
Synthesis and Identification of New N,N-Disubstituted Thiourea, and Thiazolidinone Scaffolds Based on Quinolone Moiety as Urease Inhibitor.
Molecules
; 27(20)2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36296723
17.
Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation.
Bioorg Chem
; 116: 105344, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34598088
18.
Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors.
Bioorg Chem
; 107: 104522, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33317838
19.
Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis.
Bioorg Chem
; 107: 104629, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482607
20.
Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases.
Bioorg Chem
; 106: 104510, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33279248