Detalhe da pesquisa
1.
Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization.
Carcinogenesis
; 40(7): 871-882, 2019 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30668646
2.
HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma.
Br J Cancer
; 120(3): 356-367, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655616
3.
Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action.
Int J Cancer
; 140(7): 1564-1570, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27997688
4.
Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma.
J Pathol
; 235(3): 466-77, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25345775
5.
Synthesis and evaluation of a (3R,6S,9S)-2-oxo-1-azabicyclo[4.3.0]nonane scaffold as a mimic of Xaa-trans-Pro in poly-L-proline type II helix conformation.
Org Biomol Chem
; 13(15): 4562-9, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25777583
6.
Transcription of click-linked DNA in human cells.
Angew Chem Int Ed Engl
; 53(9): 2362-5, 2014 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24452865
7.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Breast Cancer Res
; 15(5): R92, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24286369
8.
Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization.
Chembiochem
; 13(11): 1628-34, 2012 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22764122
9.
Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma.
Sci Rep
; 12(1): 7802, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35610242
10.
HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.
J Biol Chem
; 285(38): 29111-27, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20659896
11.
Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.
Mol Cancer
; 10: 72, 2011 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21668989
12.
A comparison of primary oesophageal squamous epithelial cells with HET-1A in organotypic culture.
Biol Cell
; 102(12): 635-44, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20843300
13.
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.
Biol Cell
; 103(1): 1-19, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20964627
14.
Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.
FEBS Lett
; 594(18): 2988-3001, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32618367
15.
p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators.
Sci Signal
; 13(630)2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371497
16.
Glycolysis Regulates Human Embryonic Stem Cell Self-Renewal under Hypoxia through HIF-2α and the Glycolytic Sensors CTBPs.
Stem Cell Reports
; 12(4): 728-742, 2019 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30880076
17.
Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines.
Cancer Res
; 66(8): 3996-4000, 2006 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16618718
18.
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells.
Oncotarget
; 9(33): 23274-23288, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29796188
19.
Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription.
Curr Biol
; 13(14): 1234-9, 2003 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12867035
20.
Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3.
FEBS Lett
; 581(30): 5831-5, 2007 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18053811