Detalhe da pesquisa
1.
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification.
Development
; 151(5)2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38358799
2.
PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase.
J Biol Chem
; 291(26): 13509-19, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27129774
3.
Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1.
Org Biomol Chem
; 14(2): 631-638, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26541578
4.
Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling.
Elife
; 132024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38780011
5.
Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci
; 33(1): e4824, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945533
6.
Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids.
Cell Rep
; 42(11): 113354, 2023 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917586
7.
A Descriptor Set for Quantitative Structure-property Relationship Prediction in Biologics.
Mol Inform
; 41(9): e2100240, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35277930
8.
Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b.
Cell Rep Med
; 3(10): 100754, 2022 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220068
9.
A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins.
Biochemistry
; 50(15): 3181-92, 2011 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21329361
10.
A T cell redirection platform for co-targeting dual antigens on solid tumors.
MAbs
; 13(1): 1933690, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34190031
11.
A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy.
EMBO Mol Med
; 13(7): e13977, 2021 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34105895
12.
Allosteric inhibition of the regulator of G protein signaling-Galpha protein-protein interaction by CCG-4986.
Mol Pharmacol
; 78(3): 360-5, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20530129
13.
Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.
Mol Pharmacol
; 78(3): 524-33, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20571077
14.
A phage-displayed single-chain Fab library optimized for rapid production of single-chain IgGs.
Protein Sci
; 29(10): 2075-2084, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32803886
15.
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen.
BMC Pharmacol
; 9: 9, 2009 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19463173
16.
Blockade of TGF-ß signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models.
Oncoimmunology
; 8(2): e1539613, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30713798
17.
A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.
MAbs
; 10(8): 1157-1167, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30183492
18.
A Suite of Biochemical Assays for Screening RNA Methyltransferase BCDIN3D.
SLAS Discov
; 22(1): 32-39, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27581605
19.
Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors.
ACS Chem Neurosci
; 6(6): 911-9, 2015 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25844489
20.
Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay.
Cell Signal
; 25(12): 2848-55, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24041654