Detalhe da pesquisa
1.
RyR2 Serine-2030 PKA Site Governs Ca2+ Release Termination and Ca2+ Alternans.
Circ Res
; 132(2): e59-e77, 2023 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583384
2.
Increased Ca2+ Transient Underlies RyR2-Related Left Ventricular Noncompaction.
Circ Res
; 133(2): 177-192, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37325910
3.
Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature
; 572(7769): 347-351, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31278385
4.
A Gating Mutation in Ryanodine Receptor Type 2 Rescues Phenotypes of Alzheimer's Disease Mouse Models by Upregulating Neuronal Autophagy.
J Neurosci
; 43(8): 1441-1454, 2023 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627208
5.
RyR2-dependent modulation of neuronal hyperactivity: A potential therapeutic target for treating Alzheimer's disease.
J Physiol
; 602(8): 1509-1518, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36866974
6.
RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers.
Biochem J
; 480(17): 1379-1395, 2023 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37492947
7.
Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.
Pflugers Arch
; 475(5): 569-581, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881190
8.
JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship.
Circ Res
; 128(4): 455-470, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334123
9.
Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart.
Circ Res
; 128(4): e63-e83, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375811
10.
RYR2-ryanodinopathies: from calcium overload to calcium deficiency.
Europace
; 25(6)2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37387319
11.
[A case of poisoning caused by head and face bite of Deinagkistrodon acutus].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 41(8): 626-629, 2023 Aug 20.
Artigo
em Chinês
| MEDLINE | ID: mdl-37667162
12.
RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation.
J Biol Chem
; 297(1): 100808, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34022226
13.
Increased RyR2 open probability induces neuronal hyperactivity and memory loss with or without Alzheimer's disease-causing gene mutations.
Alzheimers Dement
; 18(11): 2088-2098, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985200
14.
The central domain of cardiac ryanodine receptor governs channel activation, regulation, and stability.
J Biol Chem
; 295(46): 15622-15635, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878990
15.
Limiting RyR2 open time prevents Alzheimer's disease-related deficits in the 3xTG-AD mouse model.
J Neurosci Res
; 99(11): 2906-2921, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34352124
16.
Two pools of IRE1α in cardiac and skeletal muscle cells.
FASEB J
; 33(8): 8892-8904, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051095
17.
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity.
Proc Natl Acad Sci U S A
; 114(5): E859-E868, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096338
18.
The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts.
J Biol Chem
; 293(35): 13650-13661, 2018 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29986885
19.
Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans.
Biochem J
; 475(1): 169-183, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29170159
20.
[Quantitative evaluation of the relationship between femoral trochlear dysplasia and the degeneration of the patellofemoral cartilage by using T2mapping].
Zhonghua Yi Xue Za Zhi
; 99(21): 1651-1655, 2019 Jun 04.
Artigo
em Chinês
| MEDLINE | ID: mdl-31189265