Detalhe da pesquisa
1.
Identification and optimisation of a pyrimidopyridone series of IRAK4 inhibitors.
Bioorg Med Chem
; 63: 116729, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439688
2.
Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors.
Bioorg Med Chem
; 28(23): 115815, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091850
3.
A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies.
Bioorg Med Chem Lett
; 20(19): 5753-6, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805031
4.
A novel series of positive modulators of the AMPA receptor: structure-based lead optimization.
Bioorg Med Chem Lett
; 20(20): 6072-5, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20817521
5.
Lowering Lipophilicity by Adding Carbon: One-Carbon Bridges of Morpholines and Piperazines.
J Med Chem
; 61(19): 8934-8943, 2018 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30189136
6.
Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.
J Med Chem
; 58(8): 3611-25, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849762